2-甲氧基雌二醇对全脑缺血大鼠HIF-1α及RTP801的作用研究(3)
第1页 |
参见附件。
[2] Greijer AE,van der Wall E. The role of hypoxia inducible factor 1(HIF-1) in hypoxia induced apoptosis[J]. J Clin Pathol,2004,57(10):1009-1014.
[3] Pulsinelli WA,Brierley JB. A new model of bilateral hemispheric ischemia in the unanesthetized rat[J]. Stroke,1979,10(3):267-272.
[4] Dahut WL,Lakhani NJ,Gulley JL,et al. Phase Ⅰ clinical trial of oral 2-methoxyestradiol,an antiangiogenic and apoptotic agent,in patients with solid tumors[J]. Cancer Biol Ther,2006,5(1):22-27.
[5] Piret JP,Mottet D,Raes M,et al. Is HIF-1α a pro- or an anti-apoptotic protein?[J]. Biochem Pharmacol,2002,64(5-6):889-892.
[6] 彭静华,李云,袁晓东,等. 2ME2对全脑缺血大鼠HIF-1α的影响[J]. 山东医药,2007,47(1):9-10.
[7] Helton R,Cui J,Scheel JR,et al. Brain-specific knock-out of hypoxia-inducible factor-1 alpha reduces rather than increases hypoxic-ischemic damage[J]. J Neurosci,2005,25(16):4099-4107.
[8] Shoshani T,Faerman A,Mett I,et al. Identification of a novel hypoxia-inducible factor 1-responsive gene,RTP801,involved in apoptosis[J]. Mol Cell Biol,2002,22(7):2283-2293.
(收稿日期:2011-09-19)
您现在查看是摘要介绍页,详见PDF附件(2782kb)。