围产儿体重下降对新生儿高间接胆红素血症的影响(1)
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[摘要] 目的 探讨围产儿体重下降对新生儿高间接胆红素血症的意义。 方法 对我院2007年2月～2011年2月收治的321例新生儿高间接胆红素血症患儿以及随机选取的190例健康新生儿作为研究对象，分别设为实验组和对照组，对两组新生儿的体重以及胆红素含量进行测定，并对其进行比较。 结果 实验组新生儿在出生后2 d开始其体重与对照组比较差异有统计学意义(P<0.05)；实验组新生儿体重降低幅度明显高于对照组(P<0.05)；对实验组新生儿体重以及其胆红素含量的相关性分析，其有明显的线性关系(r=0.873，P<0.05)。 结论 围产儿体重下降是新生儿高间接胆红素血症发生的一重要影响因素，在对新生儿的护理以及保健中应当注意其体重的减轻情况，并对出现体重降低的患儿进行适当的治疗，以降低新生儿高间接胆红素血症的发生。
[关键词] 胆红素；新生儿；体重
[中图分类号] R722.1 [文献标识码] B [文章编号] 1673-9701(2012)02-0013-02
The impact of perinatal neonatal weight loss on indirect hyperbilirubinemia
CHEN Suping
Department of Neonatology, Shaoxing County Central Hospital in Zhejiang Province, Shaoxing 312000, China
[Abstract] Objective To investigate the significance of perinatal loss of weight on neonatal indirect hyperbilirubinemia. Methods From February 2007 to February 2011, the hospital treated 321 cases of children with high indirect hyperbilirubinemia, and randomly selected 190 cases of healthy newborns as subjects of study, divided into experimental group and control group, the newborn's weight and bilirubin of two groups were determined and compared. Results After the birth of 2d body weight of the experimental group comparing with the control group had significant differences (P<0.05); Lower birth weight range of the experimental group was significantly higher (P<0.05); The experimental group infants weight and relevance of its analysis of bilirubin levels, which have significant linear relationship (r=0.873, P<0.05). Conclusion Perinatal loss of weight is one important factor for the occurrence of neonatal indirect hyperbilirubinemia in neonatal care, and care should be taken to mitigate the situation of their body weight, and weight loss occurs in patients appropriate treatment to reduce the occurrence of neonatal indirect hyperbilirubinemia.
[Key words] Bilirubin; Newborn; Weight
黄疸作为新生儿主要面对的问题，Hedderson MM等[1]研究发现约有近一半的足月儿以及80%的早产儿会出现黄疸症状。Salas AA等[2]对新生儿黄疸的研究发现其主要病因为窒息、早产、ABO溶血以及代谢性疾病等。由于胆红素具有神经毒性，故新生儿在出生1周内受胆红素的毒性危险较大。故如何采取有效措施降低新生儿出生后期高胆红素血症，降低新生儿黄疸是提高新生儿生存的重要方向。我院通过对本院高胆红素血症患儿的临床研究，发现体重的降低与高胆红素血症的发生有一定关系 ......
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