脑梗死合并代谢综合征的临床研究(1)
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[摘要] 目的 观察脑梗死合并代谢综合征(MS)的临床特征并探讨MS与脑梗死危险因素的关联性。 方法 120例脑梗死患者中65例MS患者列入研究组，55例非MS者列入对照组，收集所有患者临床资料，比较两组患者基本资料、神经功能缺损评分和相关生化指标。 结果 两组患者在性别和年龄方面差异无统计学意义(P>0.05)，但研究组发病率和神经功能缺损评分显著高于对照组，差异均有统计学意义(P<0.05)；研究组患者C-反应蛋白、尿酸、纤维蛋白原指标均显著高于对照组(P<0.05)，空腹血糖指标极显著高于对照组(P<0.01)。 结论 MS临床发病率高、患者神经功能缺损严重，与脑梗死的相关危险因素存在关联性，应加强预防与控制。
[关键词] 脑梗死；代谢综合征；临床研究
[中图分类号] R743.33；R589 [文献标识码] B [文章编号] 1673-9701(2012)02-0029-02
Clinical study of cerebral infarction with metabolic syndrome
CHEN Haiyan
Department of Neurology, Xiangshan People's Hospital in Zhejiang Province, Xiangshan 315700, China
[Abstract] Objective To observe the clinical features of cerebral infarction with metabolic syndrome (MS), and discuss the relationship between MS and risk factors for cerebral infarction. Methods Sixty-five MS cases in 120 cerebral infarction patients were distributed into study group and other 55 cases without MS were distributed into control group. Clinical informations of all the patients were collected and the basic information, neurological deficit scores and biochemical indicators of two groups were compared. Results Two groups had no significant difference in sex and age (P>0.05). Study group had a higher incidence than control group and average patients’ neurological deficit score in study group was significantly higher than control group (P<0.05). The C-reactive protein, uric acid and fibrinogen in study group were significantly higher than those of control group (P<0.05), and fasting blood sugar level was more significantly higher than that of control group (P<0.01). Conclusion MS had a high incidence and patients with MS had severe neurological deficits. It had relationship with risk factors for cerebral infarction and should be strengthened for prevention and control.
[Key words] Cerebral infarction; Metabolic syndrome; Clinical study
脑梗死(cerebral infarction)又称为“缺血性脑卒中”，因局部脑组织的血液循环受阻，造成脑部缺氧缺血而诱发一系列不良临床反应，比如头痛头晕、恶心呕吐、偏瘫等。脑梗死对患者的生命健康威胁较大，而代谢综合征(metabolic syndrome，MS)又是脑梗死患者的常见并发症，即多种代谢性疾病综合发生的症侯群，成为动脉粥样硬化、脑梗死等心血管类疾病的高危因子[1]。统计表明，脑梗死合并MS患者发生卒中的可能性是非MS患者的3倍，而死亡率可达非MS患者的5～6倍[2]。本文观察了脑梗死合并MS的临床特征，并探讨MS与脑梗死危险因素的关联性 ......
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