慢性阻塞性肺疾病患者血浆CRP浓度变化研究
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[摘要] 目的 探讨血浆C-反应蛋白(CRP)在慢性阻塞性肺疾病(COPD)急性加重期患者中的浓度变化，从而观察血浆C-反应蛋白与慢性阻塞性肺疾病病情严重程度的相关性。 方法 选择2009年1月~2010年1月在我院住院的慢性阻塞性肺疾病急性加重期患者68例，设为慢性阻塞性肺疾病组，正常对照组49例；采取免疫比浊法测定血浆C-反应蛋白，所有患者均测定肺功能。 结果 慢性阻塞性肺疾病组血浆C-反应蛋白浓度明显高于正常对照组，且均随慢性阻塞性肺疾病严重程度的加重而显著增加。 结论 血浆C-反应蛋白水平在慢性阻塞性肺疾病患者中明显升高，且与慢性阻塞性肺疾病的严重程度有明显相关性。
[关键词] 慢性阻塞性肺疾病；C-反应蛋白
[中图分类号] R563.3 [文献标识码] B [文章编号] 1673-9701(2012)02-0150-02
The study of serum C-Reactive protein in patients with chronic obstructive pulmonary disease
YANG Xin WANG Di
Department of Respiratory The Fourth People’s Hospital of Shenyang，Shenyang 110031，China
[Abstract] Objective To study the change of serum CRP concentration in patients with chronic obstructive pulmonary disease and to investigate the correlation between CRP and the seriousness of COPD. Methods All of 68 patients with COPD came from our hospital from January 2009 to January 2010. Serum CRP were detected by Immune Turbidimtry.All patients were tested pulmonary function. Results The serum CRP concentration in patient group was significantly higher than that of the control group and increased with the seriousness of COPD. Conclusion The serum concentration of CRP increases significantly in patients with COPD and has obvious correlations with the seriousness of COPD.
[Key words] Chronic obstructive pulmonary disease;C-reactive protein
慢性阻塞性肺疾病是呼吸系统疾病中的常见病和多发病，患病率和病死率均居高不下。急性加重期常由于细菌或病毒感染所致。本文探讨了血浆C-反应蛋白在慢性阻塞性肺疾病急性加重期患者中的浓度变化 ......
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