伏立康唑注射液治疗ICU侵袭性真菌感染的疗效与安全性
[摘要] 目的 评价伏立康唑治疗ICU侵袭性真菌感染的有效性与安全性。 方法 收集我院2010年1月~2011年10月的ICU侵袭性真菌感染患者40例,均给予伏立康唑,观察症状体征、实验室及细菌学指标,并对该药疗效与副作用进行描述与评价。 结果 在本组40例患者中,痊愈6例,显效27例,进步4例,无效3例,总有效率82.5%;40例患者中9例发生伏立康唑相关不良反应事件,不良事件发生率22.5%,经治疗后均能好转。 结论 伏立康唑治疗ICU侵袭性真菌感染具有广谱抗真菌功效,同时它所引发的不良事件较少且多能耐受。[关键词] 侵袭性真菌感染;ICU;伏立康唑;疗效;安全性
[中图分类号] R519 [文献标识码] B [文章编号] 1673-9701(2012)02-0159-02
Efficacy and security of voriconazole injection in the treatment of invasive fungal infections
JIANG Songhua
ICU,the Second Hospital of Changchun City,Changchun 130061,China
[Abstract] Objective To evaluate the efficacy and security of voriconazole injection in the treatment of patients with invasive fungal infections. Methods Chosed 40 ICU patients with invasive fungal infections treated in our hospital from January 2010 to October 2011. All cases received the voriconazole injection. Observed the symptoms ......
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