盐敏感性高血压患者血压变异性分析(1)
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[摘要] 目的 探讨盐敏感高血压患者动态血压和血压变异性特点及临床意义。 方法 150 例原发性高血压病患者分为盐敏感性高血压组81 例和非盐敏感性高血压组69 例 ，两组患者均进行24 h动态血压监测后，对两组的血压均值和血压变异性进行分析和比较。 结果 盐敏感性高血压组的N—SBP、N—DBP均显著高于NSS组(P < 0.01、0.05)。盐敏感性高血压组的 24 h的SBPV、D—SBPV、N—SBPV、N—DBPV显著高于非盐敏感性高血压组(P < 0.01)。 结论 血压变异性增高是盐敏感性高血压特点之一，为盐敏感性高血压患者个体化治疗提供了客观依据。
[关键词] 高血压；盐敏感；血压变异性
[中图分类号] R544.1 [文献标识码] B [文章编号] 1673—9701(2012)24—0044—02
The analysis of blood pressure variability in salt sensitive hypertensive patients
TANG Yantian1 WU Qi1 HU Ze1 ZHANG Shun''an1 YAO Xueyan2
1.Department of Cardiology， the People’s Hospital of Beilun District of Ningbo City，Ningbo 315800， China； 2.Department of Cardiology， the First Affiliated Hospital of Medicine College of Zhejiang University， Hangzhou 310003， China
[Abstract] Objective To investigate the characteristics of blood pressure variability (BPV) in salt sensitive hypertensive patients. Methods All of 150 hypertensive patients underwent acute saline loading test to determine salt sensitive(SS) hypertensive patients. 81 subjects were defined as SS hypertensive patients and the others non salt sensitive (NSS) hypertensive patients. All patients were undergone 24 hours ambulatory blood pressure monitoring. Results N—SBP， N—DBP in SS group were higher than those in NSS group (P < 0.01， 0.05). Compared with NSS group， 24 SBPV， D—SBPV， N—SBPV， N—DBPV in SS group were increased (P < 0.01). Conclusion It’s suggested that the increased BPV is a important clinical features for salt sensitive hypertension. It provided objective evidences for individualized pressure lowering treatment of salt sensitive hypertensive patients.
[Key words] Hypertension； Salt sensitive； Blood pressure variability ......
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