新疆和田地区60例泌尿系结石成分分析(1)
[摘要] 目的 使用红外光谱法分析和田地区泌尿系结石成分的构成，为临床预防和治疗提供依据。 方法 对60例尿路结石标本进行化学成分测定，并结合临床资料进行分析。 结果 结石分析显示单纯性结石33例(55.00%)。其中草酸钙结石18例(30.00%)，尿酸结石7例(11.67%)，尿酸铵结石8例(13.33%)。混合性结石27例(45.00%)，尿酸铵+草酸钙结石12例(20.00%)，草酸钙+碳酸磷灰石13例(21.67%)，尿酸铵+碳酸磷灰石+磷酸铵镁2例(3.33%)。所有结石中草酸钙检出率最高，为72%，10岁以下儿童结石中尿酸铵检出率最高，为86%。 结论 新疆和田地区尿石症患者结石成分总体以草酸钙为主，儿童结石成分则以尿酸铵结石为主，有其地域特点。
[关键词] 尿石症；结石成分；红外光谱
[中图分类号] R691.4 [文献标识码] B [文章编号] 1673-9701(2015)20-0023-03
, http://www.100md.com
Analysis of chemical composition of urinary stones in 60 patients in Hetian area of Xinjiang
ZHU Weicong WANG Wei LIU Yuexin
Department of Urology Surgery，the Affiliated Beijing Tongren Hospital， Capital Medical University， Beijing 100730， China
[Abstract] Objective To analyze the constitute components of Hetian prefecture urinary calculi by infrared spectroscopy for providing the basis for clinical prevention and treatment. Methods Chemical analysis was carried out on 60 urinary stones samples. The chemical constituents of stones were analyzed with the clinical data. Results Analysis of stones showed 33 cases(55%) of purestone. There were 18 cases(30%) of calcium oxalate stones，7 cases(11.67%) of uric acid，8 cases(13.33%) of ammonium urate. Besides，there were 27 cases(45.00%) of mixed stone， 12 cases (20.00%) of ammonium urate with calcium oxalate， 13 cases(21.67%) of calcium oxalate with calcium phosphate，and 2 cases of infection stone(3.33%). All the highest calcium oxalate stone detection rate was 72%. children under the age of 10 had highest rate of urinary calcium ammonium 86%. Conclusion The major component of urinary stone in Hetian is calcium oxalate.In children under the age of 10，the most commonly major component of urinary stone is ammonium urate. The chemical composition of urinary stone in Hetian area has its regional characteristics.
, 百拇医药
[Key words] Urolithiasis；Stone composition；Infrared spectroscopy
南疆地区有较高的结石发病率[1]。该地区在气候特征、膳食结构、生活习惯、民族构成上与内地相比有较大不同，结石成分上可能存在差异。为进一步掌握该地区泌尿系结石的特点，为临床预防和治疗提供依据，我们采用红外光谱法对该地区60例结石标本进行成分分析，现将结果报道如下。
1 资料与方法
1.1 一般资料
收集和田地区2012年5月～2015年1月维吾尔族患者中经体外冲击波碎石术、输尿管镜下碎石取石术、经皮肾镜取石术及开放手术取得的尿路结石标本共60例。
1.2 检测方法
, http://www.100md.com
结石采用天津蓝奠德科学仪器有限公司的结石红外光谱自动分析系统进行检测。测试前，将结石用清水洗净晾干后，放入100℃～700℃烘箱内烘干。取出约1 mg结石样品粉末与事先充分干燥的200 mg纯溴化钾充分混合，再放入玛瑙乳钵内研碎至2 μm以下。随后将混合物用压片机加压，制成半透明片，迅速置入红外光谱槽中扫描。电脑绘制谱图，自动解析和报告结石成分。
2 结果
2.1 结石成分分析
单纯性结石33例，占55.00%。其中草酸钙结石18例，占30.00%；尿酸结石7例，占11.67%；尿酸铵结石8例，占13.33%。混合性结石27例，占45.00%。尿酸铵+草酸钙结石12例，占20.00%；草酸钙+碳酸磷灰石13例，占21.67%；尿酸铵+碳酸磷灰石+磷酸铵镁2例，占3.33%。见表1、2。, 百拇医药(朱维聪 王伟 刘跃新)
[关键词] 尿石症；结石成分；红外光谱
[中图分类号] R691.4 [文献标识码] B [文章编号] 1673-9701(2015)20-0023-03
, http://www.100md.com
Analysis of chemical composition of urinary stones in 60 patients in Hetian area of Xinjiang
ZHU Weicong WANG Wei LIU Yuexin
Department of Urology Surgery，the Affiliated Beijing Tongren Hospital， Capital Medical University， Beijing 100730， China
[Abstract] Objective To analyze the constitute components of Hetian prefecture urinary calculi by infrared spectroscopy for providing the basis for clinical prevention and treatment. Methods Chemical analysis was carried out on 60 urinary stones samples. The chemical constituents of stones were analyzed with the clinical data. Results Analysis of stones showed 33 cases(55%) of purestone. There were 18 cases(30%) of calcium oxalate stones，7 cases(11.67%) of uric acid，8 cases(13.33%) of ammonium urate. Besides，there were 27 cases(45.00%) of mixed stone， 12 cases (20.00%) of ammonium urate with calcium oxalate， 13 cases(21.67%) of calcium oxalate with calcium phosphate，and 2 cases of infection stone(3.33%). All the highest calcium oxalate stone detection rate was 72%. children under the age of 10 had highest rate of urinary calcium ammonium 86%. Conclusion The major component of urinary stone in Hetian is calcium oxalate.In children under the age of 10，the most commonly major component of urinary stone is ammonium urate. The chemical composition of urinary stone in Hetian area has its regional characteristics.
, 百拇医药
[Key words] Urolithiasis；Stone composition；Infrared spectroscopy
南疆地区有较高的结石发病率[1]。该地区在气候特征、膳食结构、生活习惯、民族构成上与内地相比有较大不同，结石成分上可能存在差异。为进一步掌握该地区泌尿系结石的特点，为临床预防和治疗提供依据，我们采用红外光谱法对该地区60例结石标本进行成分分析，现将结果报道如下。
1 资料与方法
1.1 一般资料
收集和田地区2012年5月～2015年1月维吾尔族患者中经体外冲击波碎石术、输尿管镜下碎石取石术、经皮肾镜取石术及开放手术取得的尿路结石标本共60例。
1.2 检测方法
, http://www.100md.com
结石采用天津蓝奠德科学仪器有限公司的结石红外光谱自动分析系统进行检测。测试前，将结石用清水洗净晾干后，放入100℃～700℃烘箱内烘干。取出约1 mg结石样品粉末与事先充分干燥的200 mg纯溴化钾充分混合，再放入玛瑙乳钵内研碎至2 μm以下。随后将混合物用压片机加压，制成半透明片，迅速置入红外光谱槽中扫描。电脑绘制谱图，自动解析和报告结石成分。
2 结果
2.1 结石成分分析
单纯性结石33例，占55.00%。其中草酸钙结石18例，占30.00%；尿酸结石7例，占11.67%；尿酸铵结石8例，占13.33%。混合性结石27例，占45.00%。尿酸铵+草酸钙结石12例，占20.00%；草酸钙+碳酸磷灰石13例，占21.67%；尿酸铵+碳酸磷灰石+磷酸铵镁2例，占3.33%。见表1、2。, 百拇医药(朱维聪 王伟 刘跃新)