钩藤碱对痴呆模型小白鼠学习记忆的干预作用研究(5)
综上所述,钩藤碱对快速老化小白鼠脑组织脑内β位点APP裂解酶、β-淀粉样蛋白前体及淀粉样蛋白沉积表达有明显的抑制作用,提示钩藤碱改善快速老化小白鼠的学习记忆力的作用机制是通过调节Aβ通路的表达等途径,我们期待本研究对未来阿尔茨海默症的治疗可以扮演重要角色。[参考文献]
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