冠心病合并左心功能不全PCI治疗的临床观察(1)
[摘要] 目的 探讨PCI治疗冠心病合并左心功能不全的临床疗效。 方法 选取2014年1月～2015年5月入住我院被诊断为冠心病合并左心功能不全(LVEF<50%)的患者52例，其中26例采取介入治疗，为介入组，26例采取药物治疗，为对照组。两组患者治疗前、治疗后6个月分别行心脏超声检查，观察两组患者左心功能指标包括LVEF、LVDd、NYHA分级的变化以及不良心血管事件。 结果 介入组与保守组比较，临床症状改善明显，NYHA分级明显提高，介入组提高率38.46%，而保守组无提高患者，且下降19.44%，差异具有统计学意义(P<0.05)。治疗后，介入组LVEF改善率(56.2±2.3)%明显高于药物组(40.1±1.6)%，差异具有统计学意义(P<0.05)；介入组LVDd为(51.2±2.1)mm明显低于保守组(54.7±2.2)mm，差异具有统计学意义(P<0.05)。介入组无一例出院后出现不良事件，而保守组出院后出现不良心血管事件发生率高，且死亡2例患者，差异有统计学意义(P<0.05)。 结论 冠心病合并左心功能不全的患者PCI治疗安全有效，可明显改善患者心功能，临床疗效显著。
[关键词] 经皮冠状动脉介入治疗；冠心病；左心功能不全
[中图分类号] R541.4 [文献标识码] B [文章编号] 1673-9701(2016)09-0082-04
[Abstract] Objective To explore the clinical effect of PCI in treating coronary heart disease with left ventricular dysfunction. Methods A total of 52 cases patients，who were in our hospital and diagnosed as coronary heart disease with left ventricular dysfunction(LVEF<50%) from January 2014 to May 2015， were selected and divided into intervention group and conservative group， with 26 cases in each group. The intervention group was treated by interventional therapy， and the conservative group was treated with drug therapy as conservative group. Before treatment and after treatment 6 months， two groups were given heart ultrasound examination， in order to observe LVEF， LVDd， NYHA and the MACE. Results Compared with the conservative group， the clinical symptoms and the NYHA grade of intervention group were significantly improved. The improvement rate of the intervention group was 38.46%， while that of the conservative group was not improved， and the rate of decrease was 19.44%. The difference between the two groups was significant(P<0.05). After treatment， the LVEF in the intervention group was(56.2±2.3)% was significantly higher than that of the conservative group(40.1±1.6)%， and the difference was statistically significant(P<0.05). The LVDd in the intervention group was(51.2±2.1)mm， which was obvionsly lower than that in the conservative group， with significant difference(P<0.05). In the intervention group， there was no case of adverse events after discharge， while the conservative group had a high incidence of adverse cardiovascular events after discharge， and 2 cases of death. The difference between the two groups was statistically significant(P<0.05). Conclusion PCI is safe and effective to treat patients with coronary heart disease with left ventricular dysfunction. PCI can significantly improve cardiac function. Its clinical curative effect is remarkable., 百拇医药(王丹丹 张志龙 时家义)
[关键词] 经皮冠状动脉介入治疗；冠心病；左心功能不全
[中图分类号] R541.4 [文献标识码] B [文章编号] 1673-9701(2016)09-0082-04
[Abstract] Objective To explore the clinical effect of PCI in treating coronary heart disease with left ventricular dysfunction. Methods A total of 52 cases patients，who were in our hospital and diagnosed as coronary heart disease with left ventricular dysfunction(LVEF<50%) from January 2014 to May 2015， were selected and divided into intervention group and conservative group， with 26 cases in each group. The intervention group was treated by interventional therapy， and the conservative group was treated with drug therapy as conservative group. Before treatment and after treatment 6 months， two groups were given heart ultrasound examination， in order to observe LVEF， LVDd， NYHA and the MACE. Results Compared with the conservative group， the clinical symptoms and the NYHA grade of intervention group were significantly improved. The improvement rate of the intervention group was 38.46%， while that of the conservative group was not improved， and the rate of decrease was 19.44%. The difference between the two groups was significant(P<0.05). After treatment， the LVEF in the intervention group was(56.2±2.3)% was significantly higher than that of the conservative group(40.1±1.6)%， and the difference was statistically significant(P<0.05). The LVDd in the intervention group was(51.2±2.1)mm， which was obvionsly lower than that in the conservative group， with significant difference(P<0.05). In the intervention group， there was no case of adverse events after discharge， while the conservative group had a high incidence of adverse cardiovascular events after discharge， and 2 cases of death. The difference between the two groups was statistically significant(P<0.05). Conclusion PCI is safe and effective to treat patients with coronary heart disease with left ventricular dysfunction. PCI can significantly improve cardiac function. Its clinical curative effect is remarkable., 百拇医药(王丹丹 张志龙 时家义)