异钩藤碱通过mTOR非依赖性途径诱导SH—SY5Y细胞自噬发生(5)
[15] Xian YF,Mao QQ,Wu JC,et al. Isorhynchophylline treatment improves the amyloid-β-induced cognitive impairment in rats via inhibition of neuronal apoptosis and tau protein hyperphosphorylation[J]. J Alzheimers Dis, 2014, 39(2):331-346.
[16] Xian YF,Su ZR,Chen JN,et al. Isorhynchophylline improves learning and memory impairments induced by D-galactose in mice[J]. Neurochem Int,2014,76:42-49.
[17] Menzies FM,Fleming A,Rubinsztein DC. Compromised autophagy and neurodegenerative diseases[J]. Nat Rev Neurosci,2015,16(6):345-357.
[18] 李治国,张继红,张锦华. mTOR通路对神经母细胞瘤SH-SY5 Y细胞自噬作用的影响[J]. 现代肿瘤医学, 2014,(10):2278-2280.
[19] Kim YC,Guan KL. mTOR:A pharmacologic target for autophagy regulation[J]. J Clin Invest,2015,125(1):25-32.
[20] Steelman LS,Chappell WH, Abrams SL, et al. Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging[J]. Aging (Albany NY),2011, 3(3):192-222.
(收稿日期:2016-03-31), http://www.100md.com(徐妍 严旺 蔡雅卫 王继业)
[16] Xian YF,Su ZR,Chen JN,et al. Isorhynchophylline improves learning and memory impairments induced by D-galactose in mice[J]. Neurochem Int,2014,76:42-49.
[17] Menzies FM,Fleming A,Rubinsztein DC. Compromised autophagy and neurodegenerative diseases[J]. Nat Rev Neurosci,2015,16(6):345-357.
[18] 李治国,张继红,张锦华. mTOR通路对神经母细胞瘤SH-SY5 Y细胞自噬作用的影响[J]. 现代肿瘤医学, 2014,(10):2278-2280.
[19] Kim YC,Guan KL. mTOR:A pharmacologic target for autophagy regulation[J]. J Clin Invest,2015,125(1):25-32.
[20] Steelman LS,Chappell WH, Abrams SL, et al. Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging[J]. Aging (Albany NY),2011, 3(3):192-222.
(收稿日期:2016-03-31), http://www.100md.com(徐妍 严旺 蔡雅卫 王继业)