胃泌素释放肽受体拮抗剂RC—3095通过抑制TLR4途径减轻小鼠肝缺血再灌注损伤的研究(5)
[15]Colletti LM,Green M. Lung and liver injury following hepatic ischemia/reperfusion in the rat is increased by exogenous lipopolysaccharide which also increases hepatic TNF production in vivo and in vitro[J]. Shock,2001, 16(4):312-319.
[16]Czepielewski RS,Porto BN,Rizzo LB,et al. Gastrin-releasing peptide receptor(GRPR) mediates chemotaxis in neutrophils[J]. Proc Natl Acad Sci USA,2012,109(2):547-552.
[17]Takeuchi O,Akira S. Pattern recognition receptors and inflammation[J]. Cell,2010,140:805-820.
[18]Yang H,Zhou H,Zhuang L,et al. Plasma membrane-bound G protein-coupled bile acid receptor attenuates liver ischemia/reperfusion injury via the inhibition of toll-like receptor 4 signaling in mice[J]. Liver Transpl,2017,23(1):63-74.
[19]Kadono K,Uchida Y,Hirao H,et al. Thrombomodulin attenuates inflammatory damage due to liver ischemia and reperfusion injury in mice in toll-like receptor 4-dependent manner[J]. Am J Transplant,2017,17(1):69-80.
[20]Xu J,Zhang X,Monestier M,et al. Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury[J]. J Immunol,2011,187:2626-2631.
(收稿日期:2016-11-9), 百拇医药(孙璐 陆叶兰 简春燕 冯慧 陈明生 曹利军)
[16]Czepielewski RS,Porto BN,Rizzo LB,et al. Gastrin-releasing peptide receptor(GRPR) mediates chemotaxis in neutrophils[J]. Proc Natl Acad Sci USA,2012,109(2):547-552.
[17]Takeuchi O,Akira S. Pattern recognition receptors and inflammation[J]. Cell,2010,140:805-820.
[18]Yang H,Zhou H,Zhuang L,et al. Plasma membrane-bound G protein-coupled bile acid receptor attenuates liver ischemia/reperfusion injury via the inhibition of toll-like receptor 4 signaling in mice[J]. Liver Transpl,2017,23(1):63-74.
[19]Kadono K,Uchida Y,Hirao H,et al. Thrombomodulin attenuates inflammatory damage due to liver ischemia and reperfusion injury in mice in toll-like receptor 4-dependent manner[J]. Am J Transplant,2017,17(1):69-80.
[20]Xu J,Zhang X,Monestier M,et al. Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury[J]. J Immunol,2011,187:2626-2631.
(收稿日期:2016-11-9), 百拇医药(孙璐 陆叶兰 简春燕 冯慧 陈明生 曹利军)