甲状腺良恶性结节在随访过程中的超声检查显示生长变化情况观察(1)
[摘要] 目的 观察甲状腺良恶性结节在随访过程中的超声检查显示生长变化情况。 方法 选取我院2015年1月～2017年1月收治的40例甲状腺切除术患者(80个结节)，依据结节性质将患者分为良性组(n=20，40个结节)和恶性组(n=20，40个结节)，统计分析两组患者结节随访征象变化、大小变化的最大径。 结果 两组患者结节大小、内部成分、微钙化之间差异显著(P<0.05)，但回声、边缘、纵横比之间差异均不显著(P>0.05)；两组患者80个结节中，增大22例，变小12例，分别占总数的27.5%、15.0%，其中增大结节的最大径显著大于非增大结节(P<0.05)，变小结节的最大径显著小于非变小结节(P<0.05)。 结论 甲状腺良恶性结节能够在随访过程中的超声检查显示生长变化情况，得到有效鉴别，值得临床充分重视。
[关键词] 甲状腺良恶性结节；随访过程；超声检查；生长变化情况
[中图分类号] R581；R445.1 [文献标识码] B [文章编号] 1673-9701(2017)12-0133-04
[Abstract] Objective To observe the changes of benign and malignant thyroid nodules showed by ultrasonography during follow-up. Methods 40 patients with thyroidectomy(80 nodules) in our hospital from January 2015 to January 2017 were enrolled in this study. These patients were divided into benign group(n=20， 40 nodules) and malignant group(n=20， 40 nodules). The follow-up signs of changes and the largest diameter of the change size in the nodules between the two groups were statistically analyzed. Results There were significant differences in nodule size， internal composition and microcalcification between the two groups(P<0.05)， but there was no significant difference in echo， edge， aspect ratio between the two groups(P>0.05). In the 80 nodules of the two groups， there were 22 cases of enlargement and 12 cases became smaller， accounting for 27.5%， 15.0% of the total number， respectively. The maximal diameter of the enlarged nodules was significantly larger than that of the non-enlarged nodules(P<0.05)， and the maximal diameter in the reduced nodules was significantly smaller than that of the non-reduced nodules(P<0.05). Conclusion Ultrasonography of thyroid benign and malignant nodules can be effectively identified in the process of showing growth changes by ultrasound， which is worthy of clinical attention.
[Key words] Thyroid benign and malignant nodules； Follow-up process； Ultrasonography； Growth changes
近年來，甲状腺结节发病率日益升高，大部分为良性结节，现阶段，高分辨率超声检查是临床对甲状腺结节进行评估过程中采用的最佳方法[1]。大部分甲状腺结节患者需要长期随访，通过对结节生长变化进行超声观察，将重要依据提供给临床从而选择治疗方案[2]。现阶段，较少有相关医学研究报道甲状腺结节的生长变化。本研究观察甲状腺良恶性结节在随访过程中的超声检查显示生长变化情况，现报道如下。
1 资料与方法
1.1 一般资料
选取我院2015年1月～2017年1月收治的40例甲状腺切除术患者(80个结节)。纳入标准：所有患者术前均接受甲状腺超声检查随访，随访时间均在1年及以上，结节大小均能够准确测量。排除标准：将结节接受过药物、射频消融治疗等患者排除在外。依据结节性质将患者分为良性组(n=20，40个结节)和恶性组(n=20，40个结节)。良性组患者中男4例，女16例；年龄15～77岁，平均(47.2±12.1)岁；随访时间1～7年，平均(2.6±0.5)年。在结节病理类型方面，腺瘤样增生结节31个，腺瘤9个。恶性组患者中男3例，女17例；年龄16～77岁，平均(47.7±12.3)岁；随访时间1～7年，平均(2.8±0.6)年。在结节病理类型方面，40个均为甲状腺乳头状癌。两组患者的性别、年龄、随访时间等一般资料比较差异均不显著(P>0.05)，具有可比性。见表1。, http://www.100md.com(江玉芳)
[关键词] 甲状腺良恶性结节；随访过程；超声检查；生长变化情况
[中图分类号] R581；R445.1 [文献标识码] B [文章编号] 1673-9701(2017)12-0133-04
[Abstract] Objective To observe the changes of benign and malignant thyroid nodules showed by ultrasonography during follow-up. Methods 40 patients with thyroidectomy(80 nodules) in our hospital from January 2015 to January 2017 were enrolled in this study. These patients were divided into benign group(n=20， 40 nodules) and malignant group(n=20， 40 nodules). The follow-up signs of changes and the largest diameter of the change size in the nodules between the two groups were statistically analyzed. Results There were significant differences in nodule size， internal composition and microcalcification between the two groups(P<0.05)， but there was no significant difference in echo， edge， aspect ratio between the two groups(P>0.05). In the 80 nodules of the two groups， there were 22 cases of enlargement and 12 cases became smaller， accounting for 27.5%， 15.0% of the total number， respectively. The maximal diameter of the enlarged nodules was significantly larger than that of the non-enlarged nodules(P<0.05)， and the maximal diameter in the reduced nodules was significantly smaller than that of the non-reduced nodules(P<0.05). Conclusion Ultrasonography of thyroid benign and malignant nodules can be effectively identified in the process of showing growth changes by ultrasound， which is worthy of clinical attention.
[Key words] Thyroid benign and malignant nodules； Follow-up process； Ultrasonography； Growth changes
近年來，甲状腺结节发病率日益升高，大部分为良性结节，现阶段，高分辨率超声检查是临床对甲状腺结节进行评估过程中采用的最佳方法[1]。大部分甲状腺结节患者需要长期随访，通过对结节生长变化进行超声观察，将重要依据提供给临床从而选择治疗方案[2]。现阶段，较少有相关医学研究报道甲状腺结节的生长变化。本研究观察甲状腺良恶性结节在随访过程中的超声检查显示生长变化情况，现报道如下。
1 资料与方法
1.1 一般资料
选取我院2015年1月～2017年1月收治的40例甲状腺切除术患者(80个结节)。纳入标准：所有患者术前均接受甲状腺超声检查随访，随访时间均在1年及以上，结节大小均能够准确测量。排除标准：将结节接受过药物、射频消融治疗等患者排除在外。依据结节性质将患者分为良性组(n=20，40个结节)和恶性组(n=20，40个结节)。良性组患者中男4例，女16例；年龄15～77岁，平均(47.2±12.1)岁；随访时间1～7年，平均(2.6±0.5)年。在结节病理类型方面，腺瘤样增生结节31个，腺瘤9个。恶性组患者中男3例，女17例；年龄16～77岁，平均(47.7±12.3)岁；随访时间1～7年，平均(2.8±0.6)年。在结节病理类型方面，40个均为甲状腺乳头状癌。两组患者的性别、年龄、随访时间等一般资料比较差异均不显著(P>0.05)，具有可比性。见表1。, http://www.100md.com(江玉芳)