[摘要] 目的 探讨高血压患者血清同型半胱氨酸水平与颈动脉硬化的关系。 方法 将86例原发性高血压患者按是否合并有同型半胱氨酸血症分为研究组和对照组，所有患者均检测血清Hcy水平、血尿酸、甘油三脂、总胆固醇、低密度脂蛋白，并采用彩色多普勒血仪影像技术，测量颈总动脉平均内膜-中层厚度(the carttiel intime-medliar thickness，IMT)。 结果 研究组的收缩压、舒张压、TC、TG、UA、LDL-C、IMT、Hcy明显优于对照组；研究组的颈动脉硬化情况明显比对照组低，差异有统计学意义(P<0.05)；线性回归分析中，颈动脉主要硬化的程度与Hcy水平呈正相关(P<0.05)。 结论 高血压患者中，Hcy水平与颈动脉粥样硬化密切相关。

    [关键词] 高血压；同型半胱氨酸；高同型半胱氨酸血症；颈动脉硬化

    [中图分类号] R544.1 [文献标识码] B [文章编号] 1673-9701(2017)14-0038-03

    [Abstract] Objective To investigate the relationship between serum homocysteine level and carotid atherosclerosis in patients with hypertension. Methods A total of 86 patients with primary hypertension were divided into study group and control group according to whether they had homocysteinamia. All patients were tested for serum Hcy levels ......