[摘要] 目的 探讨还原型谷胱甘肽联合介入治疗对原发性肝癌疗效及肝功能的影响。 方法 选取2014年6月～2017年3月我院肿瘤科收治的71例原发性肝癌患者，随机分为观察组(还原型谷胱甘肽联合介入治疗)36例、对照组(常规药物联合介入治疗)35例，比较两组肝功能指标及疗效。 结果 治疗前，两组谷丙转氨酶(ALT)、谷草转氨酶(AST)、碱性磷酸酶(ALP)、总胆红素(TBIL)水平比较差异无统计学意义(P>0.05)；治疗后，观察组各项肝功能指标均优于对照组，差异具有统计学意义(P<0.05)。观察组治疗有效率为86.11%，明显高于对照组的62.86%，差异具有统计学意义(P<0.05)。 结论 还原型谷胱甘肽能改善原发性肝癌患者接受介入治疗引起的肝功能损伤，提高治疗的有效性及安全性，值得临床推广采用。

    [关键词] 还原型谷胱甘肽；介入治疗；原发性肝癌；肝功能

    [中图分类号] R735.7 [文献标识码] A [文章编号] 1673-9701(2017)30-0004-04

    [Abstract] Objective To investigate the effect of reduced glutathione combined with interventional therapy on primary liver cancer and liver function. Methods 71 patients with primary liver cancer who were admitted to the department of Oncology in our hospital from June 2014 to March 2017 were selected. They were randomly divided into 36 cases in the observation group(reduced glutathione combined with interventional therapy) ......