[摘要] 目的 分析术前纤维蛋白原(FIB)、D-二聚体(D-D)水平对胃肠道间质瘤(GIST)患者预后的预测价值。 方法 选取2012年1月～2014年4月在我院诊治的80例GIST患者为研究对象，对所有患者行手术干预，术后随访3年，调查患者术后3年的一般资料及总生存率，并分析影响GIST患者预后的主要因素。 结果 GIST患者术后三年的总生存率为75%，经单因素分析发现，患者的美国国立卫生院(NIH)危险分级、FIB水平、D-D水平及癌胚抗原(CEA)水平可显著影响患者预后(P<0.05)；经Cox回归分析发现，FIB及D-D水平是影响GIST患者预后的主要因素。 结论 术前FIB及D-D水平对GIST患者的预后有较高预测价值。

    [关键词] 胃肠道间质瘤；纤维蛋白原；D-二聚体；预测价值

    [中图分类号] R735 [文献标识码] A [文章编号] 1673-9701(2018)18-0027-03

    [Abstract] Objective To analyze the predictive value of preoperative fibrinogen(FIB)and D-dimer(D-D)levels in patients with gastrointestinal stromal tumors(GIST). Methods 80 patients with GIST who were diagnosed and treated in our hospital from January 2012 to April 2014 were selected as the study subjects. All patients underwent surgical intervention. The patients were followed up for 3 years. The general data and overall survival rate after 3 years of operation were investigated ......