总之，早期强化胰岛素治疗儿童脓毒症显著优于常规胰岛素治疗，能降低血清D-乳酸和PCT指标，保持肠黏膜结构与功能完整，使肠黏膜的通透性降低对肠黏膜屏障功能的起保护作用。

    [参考文献]

    [1]Shapiro N，Howell MD，Bates DW，et al. The association of sepsis syndrome and organ dysfunction with mortality in emergency department patients with suspected in fection[J]. Ann Emerg Med，2006，48(5)：583-590.

    [2]Antonopoulou A，Giamarellos BEJ. Immunomodulation in sepsis state of the art and future perspective[J]. Immunotherapy ......