基于BDNF假说的度洛西汀治疗抑郁症的相关研究(4)
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[22] Mikoteit T，Beck J， Eckert A，et al. High baseline BDNF serum levels and early psychopathological improvement are predictive of treatment outcome in major depression[J].Psychopharmacology(Berl)，2014，231(15)：2955-2965.
[23] Fornaro M，Escelsior A，Rocchi G，et al. BDNF plasma levels variations in major depressed patients receiving duloxetine[J]. Neurol Sci，2015，36(5)：729-734.
[24] Mikoteit T，Hemmeter U，Eckert A，et al. Improved alertness is associated with early increase in serum brain-derived neurotrophic factor and antidepressant treatment outcome in major depression[J]. Neuropsychobiology，2015， 72(1)：16-28.
[25] Jiang H，Chen S，Li C，et al. The serum protein levels of the tPA-BDNF pathway are implicated in depression and antidepressant treatment[J]. Transl Psychiatry，2017，7(4)：e1079.
(收稿日期：2018-07-27), http://www.100md.com(周和统 黄满丽)
[20] Engel D，Zomkowski AD，Lieberknecht V，et al. Chronic administration of duloxetine and mirtazapine downregulates proapoptotic proteins and upregulates neurotrophin gene expression in the hippocampus and cerebral cortex of mice[J]. J Psychiatr Res，2013，47(6)：802-808.
[21] Xu H，Zhang Y，Zhang F，et al. Effects of duloxetine treatment on cognitive flexibility and BDNF expression in the mPFC of adult male mice exposed to social stress during adolescence[J]. Front Mol Neurosci，2016，9：95.
[22] Mikoteit T，Beck J， Eckert A，et al. High baseline BDNF serum levels and early psychopathological improvement are predictive of treatment outcome in major depression[J].Psychopharmacology(Berl)，2014，231(15)：2955-2965.
[23] Fornaro M，Escelsior A，Rocchi G，et al. BDNF plasma levels variations in major depressed patients receiving duloxetine[J]. Neurol Sci，2015，36(5)：729-734.
[24] Mikoteit T，Hemmeter U，Eckert A，et al. Improved alertness is associated with early increase in serum brain-derived neurotrophic factor and antidepressant treatment outcome in major depression[J]. Neuropsychobiology，2015， 72(1)：16-28.
[25] Jiang H，Chen S，Li C，et al. The serum protein levels of the tPA-BDNF pathway are implicated in depression and antidepressant treatment[J]. Transl Psychiatry，2017，7(4)：e1079.
(收稿日期：2018-07-27), http://www.100md.com(周和统 黄满丽)