急性白血病RAD50基因多态性研究(4)
[18] Lee JH,Mand MR,Deshpande RA,et al. Ataxia Telangiectasia Mutated(ATM)Kinase Activity is regulated by ATP.Driven conformationaI changes in the Mrell/Rad50/Nbsl f MRN)Complex[J].J Biol Chem,2013,288(18):12840-12851.
[19] Fan C,Zhang J,Ouyang T,et al. RAD50 germline mutations are associated with poor survival in BRCA1/2-negative breast cancer patients[J]. Cancer,2018,143(8):1935-1942.
[20] 严睿成,王君,黄子真. 突变型Rad50蛋白增强放射线对鼻咽癌细胞株CNEl的杀伤作用[J]. 中华耳鼻咽头颈外科杂志,2016,51(10):746-750.
[21] Rhee JG,Li D,Suntharalingam M,et al. Radiosensitization of head/neck sqaumous cell carcinoma by adenovirus-mediated expression of the Nbs1 protein[J]. International Journal of Radiation Oncology Biology Physics,2007,67(1):273-278.
[22] Travis HS,John HJ. The MRE11 complex:Starting from the ends[J]. Nat Rev Mol Cell Biol,2011,12(2):90-103.
[23] Karanika S,Karantanos T,Li L,et al. DNA damage response and prostate cancer: Defects,regulation and therapeutic implications[J].Oncogene,2015,34(22):2815-2822.
[24] 徐忠偉,王凤梅,王聪聪. 钠钾ATP酶抑制剂通过调节DNA损伤感应复合体Mre11/Rad50/Nbs1的表达诱导肝癌HepG2细胞周期阻滞[J]. 中国药理学通报,2016, 32(3):323-327.
(收稿日期:2019-04-23), 百拇医药(吴小乐 谢海啸 吴长春 胡王强 陈坚)
[19] Fan C,Zhang J,Ouyang T,et al. RAD50 germline mutations are associated with poor survival in BRCA1/2-negative breast cancer patients[J]. Cancer,2018,143(8):1935-1942.
[20] 严睿成,王君,黄子真. 突变型Rad50蛋白增强放射线对鼻咽癌细胞株CNEl的杀伤作用[J]. 中华耳鼻咽头颈外科杂志,2016,51(10):746-750.
[21] Rhee JG,Li D,Suntharalingam M,et al. Radiosensitization of head/neck sqaumous cell carcinoma by adenovirus-mediated expression of the Nbs1 protein[J]. International Journal of Radiation Oncology Biology Physics,2007,67(1):273-278.
[22] Travis HS,John HJ. The MRE11 complex:Starting from the ends[J]. Nat Rev Mol Cell Biol,2011,12(2):90-103.
[23] Karanika S,Karantanos T,Li L,et al. DNA damage response and prostate cancer: Defects,regulation and therapeutic implications[J].Oncogene,2015,34(22):2815-2822.
[24] 徐忠偉,王凤梅,王聪聪. 钠钾ATP酶抑制剂通过调节DNA损伤感应复合体Mre11/Rad50/Nbs1的表达诱导肝癌HepG2细胞周期阻滞[J]. 中国药理学通报,2016, 32(3):323-327.
(收稿日期:2019-04-23), 百拇医药(吴小乐 谢海啸 吴长春 胡王强 陈坚)