健脾化痰法治疗脾虚型支气管哮喘疗效观察(1)
[摘要] 目的 探讨健脾化痰法治疗脾虚型支气管哮喘的临床疗效。 方法 回顾分析浙江中医药大学附属温州中医院2017年5月～2018年8月收治的60例脾虚型支气管哮喘的临床资料，随机分为治疗组和对照组。治疗组30例采用以健脾化痰法为治则的中药汤剂联合西药舒利迭治疗，对照组30例单用舒利迭治疗，比较两组中医证候疗效、单项中医证候积分、ACT评分。 结果 治疗组在总体疗效分布、显效率方面优于对照组(P<0.05)，在临床症状改善方面，对比两组咳嗽、咳痰、胸闷、喘息等哮喘脾虚型主症方面，两者无显著差异(P>0.05)，但在改善胃纳、乏力、便溏等次症方面，治疗组明显优于对照组(P<0.05)。在ACT评分方面，治疗组改善更明显(P<0.05)。 结论 健脾化痰法治疗脾虚型支气管哮喘疗效显著，能显著改善哮喘患者的全身症状，提高患者的ACT评分，说明中医在治疗支气管哮喘时有一定的优势，值得在临床推广。
[关键词] 支气管哮喘;脾虚;健脾化痰法;中医药治疗
[Abstract] Objective To explore the clinical effect of the spleen strengthening and phlegm reducing method in the treatment of bronchial asthma with spleen deficiency. Methods The clinical data of 60 patients with bronchial asthma with spleen deficiency treated in Wenzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine from May 2017 to August 2018 were analyzed retrospectively and randomly divided into the treatment group and the control group. Thirty patients in the treatment group were treated with traditional Chinese medicine decoction based on spleen strengthening and phlegm reducing combined with western medicine sullipid， and 30 patients in the control group were treated with sullipid alone. The efficacy of TCM syndromes， single TCM syndrome points and ACT scores were compared between the two groups. Results The treatment group was superior to the control group in terms of the overall efficacy distribution and significant effective rate(P<0.05). In terms of improvement of clinical symptoms， the two groups were not significantly different in the main symptoms of asthma with spleen deficiency such as cough， sputum， chest tightness and wheezing(P>0.05)， but the treatment group was significantly better than the control group in the improvement of gastric appetite， fatigue and stool symptoms(P<0.05). In terms of ACT scores， the improvement in the treatment group was more significant(P<0.05). Conclusion The method of spleen strengthening and phlegm reducing is effective in treating bronchial asthma with spleen deficiency， and it can significantly improve the systemic symptoms of patients with asthma and increase the ACT scores of patients. This shows that traditional Chinese medicine has certain advantages in the treatment of bronchial asthma and is worthy of clinical promotion.
[Key words] Bronchial asthma; Spleen deficiency; Spleen strengthening and phlegm removing; Traditional Chinese medicine treatment
支氣管哮喘(bronchial asthma，简称哮喘)是临床常见的慢性呼吸系统疾病，常表现为反复发作性喘息、胸闷、气急或咳嗽咳痰等症状，多在夜间和(或)凌晨发生。2010年CARE研究结果显示：我国14岁以上人群哮喘患病率为1.24%[1]，总人数约3000万，因哮喘反复发作不仅给患者带来身心损害，也给社会造成严重的经济负担。复方吸入制剂已成为控制哮喘发作的主要药物，但其存在一定的不良反应，包括声音嘶哑、鹅口疮、影响身高发育等[2]。哮喘中医认为其病因病机主要在痰，在治疗上从肺、从脾、从肾论治，而脾为生痰之源，在哮喘治疗中占据重要地位，因此本临床研究随机选取支气管哮喘非急性发作患者，拟健脾化痰法，方以六君子汤加味，对比单用舒利迭，观察治疗前后两组ACT评分、临床疗效、中医证候积分的变化情况，现报道如下。, http://www.100md.com(潘锟镭 张妤婷 李献超)
[关键词] 支气管哮喘;脾虚;健脾化痰法;中医药治疗
[Abstract] Objective To explore the clinical effect of the spleen strengthening and phlegm reducing method in the treatment of bronchial asthma with spleen deficiency. Methods The clinical data of 60 patients with bronchial asthma with spleen deficiency treated in Wenzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine from May 2017 to August 2018 were analyzed retrospectively and randomly divided into the treatment group and the control group. Thirty patients in the treatment group were treated with traditional Chinese medicine decoction based on spleen strengthening and phlegm reducing combined with western medicine sullipid， and 30 patients in the control group were treated with sullipid alone. The efficacy of TCM syndromes， single TCM syndrome points and ACT scores were compared between the two groups. Results The treatment group was superior to the control group in terms of the overall efficacy distribution and significant effective rate(P<0.05). In terms of improvement of clinical symptoms， the two groups were not significantly different in the main symptoms of asthma with spleen deficiency such as cough， sputum， chest tightness and wheezing(P>0.05)， but the treatment group was significantly better than the control group in the improvement of gastric appetite， fatigue and stool symptoms(P<0.05). In terms of ACT scores， the improvement in the treatment group was more significant(P<0.05). Conclusion The method of spleen strengthening and phlegm reducing is effective in treating bronchial asthma with spleen deficiency， and it can significantly improve the systemic symptoms of patients with asthma and increase the ACT scores of patients. This shows that traditional Chinese medicine has certain advantages in the treatment of bronchial asthma and is worthy of clinical promotion.
[Key words] Bronchial asthma; Spleen deficiency; Spleen strengthening and phlegm removing; Traditional Chinese medicine treatment
支氣管哮喘(bronchial asthma，简称哮喘)是临床常见的慢性呼吸系统疾病，常表现为反复发作性喘息、胸闷、气急或咳嗽咳痰等症状，多在夜间和(或)凌晨发生。2010年CARE研究结果显示：我国14岁以上人群哮喘患病率为1.24%[1]，总人数约3000万，因哮喘反复发作不仅给患者带来身心损害，也给社会造成严重的经济负担。复方吸入制剂已成为控制哮喘发作的主要药物，但其存在一定的不良反应，包括声音嘶哑、鹅口疮、影响身高发育等[2]。哮喘中医认为其病因病机主要在痰，在治疗上从肺、从脾、从肾论治，而脾为生痰之源，在哮喘治疗中占据重要地位，因此本临床研究随机选取支气管哮喘非急性发作患者，拟健脾化痰法，方以六君子汤加味，对比单用舒利迭，观察治疗前后两组ACT评分、临床疗效、中医证候积分的变化情况，现报道如下。, http://www.100md.com(潘锟镭 张妤婷 李献超)
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