经尿道等离子电切术联合膀胱灌注治疗腺性膀胱炎的效果分析(1)
[摘要] 目的 探討经尿道等离子电切术联合膀胱灌注治疗腺性膀胱炎的效果。 方法 选取2015年1月～2018年12月拟行经尿道等离子电切术治疗的腺性膀胱炎患者70例，随机分为联合组与单纯组，每组35例。单纯组给予单纯经尿道等离子电切术，联合组在对照组经尿道等离子电切术基础上加膀胱灌注治疗，采用40 mg吡柔比星针+40 mL注射用水进行膀胱灌注，1次/周，连用8周，后改为1次/4周，连用10个月。观察并比较两组患者术中术后并发症发生率，评估术后3个月的临床疗效，并随访1年比较其复发率。 结果 单纯组和联合组患者分别发生术中术后并发症1例(2.86%)和3例(8.57%)，两组患者术中术后并发症的发生率比较差异无统计学意义(χ2=0.270，P>0.05)。术后3个月，联合组患者临床总有效率(94.29%)明显高于单纯组(77.14%)，差异有统计学意义(χ2=4.201，P<0.05)。术后随访1年，联合组和单纯组患者分别复发3例(8.57%)和10例(28.57%)，联合组患者术后复发率低于单纯组，差异有统计学意义(χ2=4.630，P<0.05)。 结论 经尿道等离子电切术联合膀胱灌注治疗腺性膀胱炎的疗效确切，且安全性较好，可有效预防病情复发。
[关键词] 腺性膀胱炎;经尿道等离子电切术;膀胱灌注;并发症;复发
[中图分类号] R699.8 [文献标识码] B [文章编号] 1673-9701(2020)18-0110-04
An efficacy analysis of transurethral plasmakinetic resection combined with intravesical instillation for cystitis glandularis
LUO Chao1 KE Mang1 HAN Zihua2
1.Department of Urology， Taizhou Hospital， Taizhou Enze Medical Center in Zhejiang Province， Linhai 317000， China; 2.Department of Urology， Enze Hospital， Taizhou Enze Medical Center in Zhejiang Province， Taizhou 318050， China
[Abstract] Objective To investigate the efficacy of transurethral plasmakinetic resection combined with intravesical instillation for cystitis glandularis. Methods From January 2015 to December 2018， seventy patients with cystitis glandularis who were treated by transurethral plasmakinetic resection were selected and randomly divided into the combined group(n=35) and the single group(n=35). Patients in the single group were treated with transurethral plasmakinetic resection alone， while patients in the combined group were treated with intravesical instillation on the basis of transurethral plasmakinetic resection in the control group. 40 mg pirarubicin plus 40 mL water for injection were used for intravesical instillation， 1 time/week， continuous use for 8 weeks， then changed to 1 time/4 weeks， continuous use for 10 months. The incidence of intraoperative and postoperative complications in the two groups were observed and compared， the clinical efficacy of three months after operation was evaluated， and the recurrence rate was compared after one year of follow-up. Results There were 2.86%(n=1) and 8.57%(n=3) of intraoperative and postoperative complications in the single group and the combined group respectively. There was no significant difference in the incidence of intraoperative and postoperative complications between the two groups(χ2=0.270， P>0.05). Three months after the operation， the total clinical effective rate(94.29%) in the combined group was significantly higher than that in the single group(77.14%)， with statistically significant differences(χ2=4.201， P<0.05). After one year of follow-up， 8.57%(n=3) and 28.57%(n=10) recurred in the combined group and the single group respectively. The postoperative recurrence rate in the combined group was lower than that in the single group， with statistically significant difference(χ2=4.630， P<0.05). Conclusion Transurethral plasmakinetic resection combined with intravesical instillation is effective and safe in the treatment of cystitis glandularis and effectively prevents recurrence of the disease., 百拇医药(罗超 柯莽 韩子华)
[关键词] 腺性膀胱炎;经尿道等离子电切术;膀胱灌注;并发症;复发
[中图分类号] R699.8 [文献标识码] B [文章编号] 1673-9701(2020)18-0110-04
An efficacy analysis of transurethral plasmakinetic resection combined with intravesical instillation for cystitis glandularis
LUO Chao1 KE Mang1 HAN Zihua2
1.Department of Urology， Taizhou Hospital， Taizhou Enze Medical Center in Zhejiang Province， Linhai 317000， China; 2.Department of Urology， Enze Hospital， Taizhou Enze Medical Center in Zhejiang Province， Taizhou 318050， China
[Abstract] Objective To investigate the efficacy of transurethral plasmakinetic resection combined with intravesical instillation for cystitis glandularis. Methods From January 2015 to December 2018， seventy patients with cystitis glandularis who were treated by transurethral plasmakinetic resection were selected and randomly divided into the combined group(n=35) and the single group(n=35). Patients in the single group were treated with transurethral plasmakinetic resection alone， while patients in the combined group were treated with intravesical instillation on the basis of transurethral plasmakinetic resection in the control group. 40 mg pirarubicin plus 40 mL water for injection were used for intravesical instillation， 1 time/week， continuous use for 8 weeks， then changed to 1 time/4 weeks， continuous use for 10 months. The incidence of intraoperative and postoperative complications in the two groups were observed and compared， the clinical efficacy of three months after operation was evaluated， and the recurrence rate was compared after one year of follow-up. Results There were 2.86%(n=1) and 8.57%(n=3) of intraoperative and postoperative complications in the single group and the combined group respectively. There was no significant difference in the incidence of intraoperative and postoperative complications between the two groups(χ2=0.270， P>0.05). Three months after the operation， the total clinical effective rate(94.29%) in the combined group was significantly higher than that in the single group(77.14%)， with statistically significant differences(χ2=4.201， P<0.05). After one year of follow-up， 8.57%(n=3) and 28.57%(n=10) recurred in the combined group and the single group respectively. The postoperative recurrence rate in the combined group was lower than that in the single group， with statistically significant difference(χ2=4.630， P<0.05). Conclusion Transurethral plasmakinetic resection combined with intravesical instillation is effective and safe in the treatment of cystitis glandularis and effectively prevents recurrence of the disease., 百拇医药(罗超 柯莽 韩子华)