[摘要] 目的 研究咳嗽变异性哮喘(CVA)患者支气管肺泡灌洗液中炎症因子的水平。 方法 选取2018年4月～2019年10月在我院诊治的CVA患者75例为观察组，选取同期在我院诊治的非CVA慢性咳嗽患者75例为对照组，收集两组患者的支气管肺泡灌洗液，检测灌洗液中炎症因子IL-5、IL-13水平。 结果 CVA组患者灌洗液中的炎症因子IL-5、IL-13水平[(189.30±100.60) pg/L、(160.52±83.70) pg/L]明显高于非CVA组[(65.80±25.60) pg/L、(40.63±23.50) pg/L]，差异有统计学意义(P<0.05)。 结论 诊断不明的慢性咳嗽患者可以行支气管肺泡灌洗液中炎症因子IL-5、IL-13水平检测以协助诊断。

    [关键词] 咳嗽变异性哮喘(CVA);支气管肺泡灌洗液;IL-5;IL-13

    [Abstract] Objective To study the level of inflammatory factors in bronchoalveolar lavage fluid in the patients with cough variant asthma(CVA). Methods A total of 75 patients with CVA who were diagnosed and treated in our outpatient clinic and inpatient ward in our hospital from April 2018 to October 2019 were randomly selected into the observation group. 75 patients with non-CVA chronic cough who were diagnosed and treated in the outpatient clinic and inpatient ward in our hospital during the same period were included in the control group. The bronchoalveolar lavage fluid was collected from both groups of patients ......