体外膜肺氧合心肺复苏后不同目标体温管理对患者脑功能的影响(1)
[摘要] 目的 探讨体外膜肺氧合心肺复苏后不同的目标体温管理对患者脑功能预后的影响。 方法 纳入2014年5月～2020年1月我院收住行体外心肺复苏的患者60例，将患者随机分为两组，其中A组30例，B组30例。A组患者的体温控制在32.0℃～34.0℃;B组患者的体温控制在34.1℃～36.0℃。通过分析比较出院时患者的存活情况、CPC评分以及并发症来评估两组患者之间的差异。 结果 60例患者中A组存活患者12例，B组存活患者10 例，两组患者存活情况比较差异无统计学意义(P>0.05)。A组患者CPC评分良好12例，B组患者CPC评分良好7例，两组患者CPC评分比较差异无统计学意义(P>0.05)。兩组患者在并发症方面比较差异无统计学意义(P>0.05)。结论 与目标体温控制在34.1℃～36.0℃相比较，体外膜肺氧合心肺复苏后的患者目标体温控制在32.0℃～34.0℃对患者的脑功能预后并无更多益处。
[关键词] 体外膜肺氧合;心肺复苏;亚低温;脑保护
[中图分类号] R459.7 [文献标识码] B [文章编号] 1673-9701(2020)21-0116-04
Impacts of different objective body temperatures management on cerebral function in patients after extracorporeal membrane oxygenation cardiopulmonary resuscitation
PAN Feiyan TONG Hongjie ZHANG Xiaoling CHEN Kun
Department of Critical Care Medicine， Jinhua Municipal Central Hospital in Zhejiang Province， Jinhua 321000， China
[Abstract] Objective To investigate the impacts of different objective body temperatures management on the prognosis of patients’ cerebral function after extracorporeal membrane oxygenation(ECMO) and cardiopulmonary resuscitation. Methods Sixty patients admitted to our hospital for extracorporeal cardiopulmonary resuscitation from May 2014 to January 2020 were included. The patients were randomly divided into two groups， including group A(n=30) and group B(n=30). The patients’ body temperatures controlled at 32.0℃-34.0℃ were divided into group A， while the patients’ body temperatures controlled at 34.1℃-36.0℃ were divided into group B. The difference between the two groups was evaluated by analyzing and comparing the survival condition of patients at discharge， cerebral performance category(CPC) score and complication. Results Among the sixty patients， there were twelve survivors in group A， ten survivors in group B， and there was no statistical difference in survival between the two groups(P>0.05). Twelve patients with high CPC scores in group A， and seven patients with high CPC scores in group B， and there was no statistical difference in CPC scores between the two groups(P>0.05). There was no difference of complication between the two groups(P>0.05). Conclusion Compared with the objective body temperatures control at 34.1℃-36.0℃， those at 32.0℃-34.0℃ after ECMO cardiopulmonary resuscitation have no more benefits to the prognosis of the cerebral function of patients.
[Key words] Extracorporeal membrane oxygenation; Cardiopulmonary resuscitation; Mild low temperature; Cerebral salvage, 百拇医药(潘飞艳 童洪杰 张晓玲 陈琨)
[关键词] 体外膜肺氧合;心肺复苏;亚低温;脑保护
[中图分类号] R459.7 [文献标识码] B [文章编号] 1673-9701(2020)21-0116-04
Impacts of different objective body temperatures management on cerebral function in patients after extracorporeal membrane oxygenation cardiopulmonary resuscitation
PAN Feiyan TONG Hongjie ZHANG Xiaoling CHEN Kun
Department of Critical Care Medicine， Jinhua Municipal Central Hospital in Zhejiang Province， Jinhua 321000， China
[Abstract] Objective To investigate the impacts of different objective body temperatures management on the prognosis of patients’ cerebral function after extracorporeal membrane oxygenation(ECMO) and cardiopulmonary resuscitation. Methods Sixty patients admitted to our hospital for extracorporeal cardiopulmonary resuscitation from May 2014 to January 2020 were included. The patients were randomly divided into two groups， including group A(n=30) and group B(n=30). The patients’ body temperatures controlled at 32.0℃-34.0℃ were divided into group A， while the patients’ body temperatures controlled at 34.1℃-36.0℃ were divided into group B. The difference between the two groups was evaluated by analyzing and comparing the survival condition of patients at discharge， cerebral performance category(CPC) score and complication. Results Among the sixty patients， there were twelve survivors in group A， ten survivors in group B， and there was no statistical difference in survival between the two groups(P>0.05). Twelve patients with high CPC scores in group A， and seven patients with high CPC scores in group B， and there was no statistical difference in CPC scores between the two groups(P>0.05). There was no difference of complication between the two groups(P>0.05). Conclusion Compared with the objective body temperatures control at 34.1℃-36.0℃， those at 32.0℃-34.0℃ after ECMO cardiopulmonary resuscitation have no more benefits to the prognosis of the cerebral function of patients.
[Key words] Extracorporeal membrane oxygenation; Cardiopulmonary resuscitation; Mild low temperature; Cerebral salvage, 百拇医药(潘飞艳 童洪杰 张晓玲 陈琨)