中医特色康复干预措施联合心理疗法在酒精性肝病合并戒断综合征患者中的应用(1)
[摘要] 目的 探討中医特色康复干预措施联合心理疗法在酒精性肝病合并戒断综合征患者中的应用。 方法 选择2018年1～12月我院感染科门诊就诊患者酒精性肝病合并戒断综合征患者74例，随机分为对照组和干预组，每组各37例。对照组患者给予以心理疗法治疗，观察组患者在对照组心理疗法基础上基于循证理论的中医特色康复干预措施，两组患者均干预8周。观察两组患者干预前后肝功能指标变化，并比较并临床效果、戒断率及复饮率。结果 治疗8周后，两组患者血清ALT和AST水平均较前显著下降(P<0.05或P<0.01)，且干预组患者下降幅度与对照组比较更显著(P<0.05);同时干预组患者临床总有效率(94.59%)较对照组(78.38%)更高，且观察组患者戒断率明显较对照组更高，复饮率较对照组更低(P<0.05)。 结论 中医特色康复干预措施联合心理疗法治疗酒精性肝病合并戒断综合征患者的效果较确切，不仅能更明显降低患者的肝功能指标，促进肝功能恢复， 且可提高酒精戒断率，降低复饮率。
[关键词] 酒精性肝病;戒断综合征;心理疗法;中医特色康复干预措施
[中图分类号] R248.9 [文献标识码] B [文章编号] 1673-9701(2020)26-0108-04
[Abstract] Objective To explore the application of traditional Chinese medicine rehabilitation interventions and psychological therapy in patients with alcoholic liver disease combined with withdrawal syndrome. Methods 74 outpatients with alcoholic liver disease combined with withdrawal syndrome treated in the department of infectious diseases from January 2018 to December 2018 were randomly divided into the control group and the intervention group， with 37 cases in each group. The control group was treated with psychotherapy， while the observation group was treated with traditional Chinese medicine based on evidence-based theory on the basis of the control group. Both groups were intervened for 8 weeks. The changes of liver function indexes before and after intervention in the two groups of patients were observed， and the clinical effects， withdrawal rates and re-drinking rates were compared. Results After 8 weeks of treatment， the levels of serum alanine aminotransferase(ALT) and aspartate aminotransferase(AST) in the two groups were significantly lower than those before treatment(P<0.05 or P<0.01)， and the decline in the intervention group was more significant than that in the control group(P<0.05). The total clinical effective rate of the intervention group(94.59%) was higher than that of the control group(78.38%)， and the withdrawal rate was significantly higher in the observation group than that in the control group， and the re-drinking rate was lower than that in the control group(P<0.05). Conclusion Traditional Chinese medicine rehabilitation intervention combined with psychological therapy is more effective in treating patients with alcoholic liver disease combined with withdrawal syndrome. It not only significantly reduces liver function indexes and promotes liver function recovery， but also increases alcohol withdrawal rate and reduces re-drinking rate., 百拇医药(章茜 孙慧伶 陈洁)
[关键词] 酒精性肝病;戒断综合征;心理疗法;中医特色康复干预措施
[中图分类号] R248.9 [文献标识码] B [文章编号] 1673-9701(2020)26-0108-04
[Abstract] Objective To explore the application of traditional Chinese medicine rehabilitation interventions and psychological therapy in patients with alcoholic liver disease combined with withdrawal syndrome. Methods 74 outpatients with alcoholic liver disease combined with withdrawal syndrome treated in the department of infectious diseases from January 2018 to December 2018 were randomly divided into the control group and the intervention group， with 37 cases in each group. The control group was treated with psychotherapy， while the observation group was treated with traditional Chinese medicine based on evidence-based theory on the basis of the control group. Both groups were intervened for 8 weeks. The changes of liver function indexes before and after intervention in the two groups of patients were observed， and the clinical effects， withdrawal rates and re-drinking rates were compared. Results After 8 weeks of treatment， the levels of serum alanine aminotransferase(ALT) and aspartate aminotransferase(AST) in the two groups were significantly lower than those before treatment(P<0.05 or P<0.01)， and the decline in the intervention group was more significant than that in the control group(P<0.05). The total clinical effective rate of the intervention group(94.59%) was higher than that of the control group(78.38%)， and the withdrawal rate was significantly higher in the observation group than that in the control group， and the re-drinking rate was lower than that in the control group(P<0.05). Conclusion Traditional Chinese medicine rehabilitation intervention combined with psychological therapy is more effective in treating patients with alcoholic liver disease combined with withdrawal syndrome. It not only significantly reduces liver function indexes and promotes liver function recovery， but also increases alcohol withdrawal rate and reduces re-drinking rate., 百拇医药(章茜 孙慧伶 陈洁)