谭雷 苏小虎 万利芹 胡筱 朱伟 刘益民 高玉杰

    [關键词] 右美托咪啶;亚麻醉剂量氯胺酮;静脉自控镇痛;晚期癌痛;镇痛效果

    [中图分类号] R734.2? ? ? ? ? [文献标识码] A? ? ? ? ? [文章编号] 1673-9701(2021)18-0129-04

    Analgesic effect of dexmedetomidine combined with sub-anesthetic ketamine intravenous patient-controlled analgesia in patients with refractory cancer pain

    TAN Lei1? ?SU Xiaohu1? ?WAN Liqin1? ?HU Xiao2? ?ZHU Wei3? ?LIU Yimin2? ?GAO Yujie2

    1.Department of Anesthesiology，First People's Hospital of Suqian，Suqian? 223800，China;2.Department of Oncology，First People's Hospital of Suqian，Suqian? 223800，China;3.Department of Anesthesiology，First Affiliated Hospital with Nanjing Medical University，Nanjing 210029，China

    [Abstract] Objective To explore the analgesic effect and safety of dexmedetomidine combined with sub-anesthetic ketamine patient-controlled intravenous analgesia(PCIA) in patients with advanced cancer pain. Methods? Sixty patients with advanced cancer pain hospitalized in the First People's Hospital of Suqian from October 2017 to November 2019 who had inadequate response to three-step analgesia or obvious adverse events were selected.They were divided into two groups using the random number table method ......