刘明明 张秀琴

    [关键词] 重度哮喘;疾病负担;表型;靶向治疗

    [中图分类号] R562? ? ? ? ? [文献标识码] A? ? ? ? ? [文章編号] 1673-9701(2021)29-0188-05

    Recent advances of disease burden and targeted therapy in severe bronchial asthma

    LIU Mingming? ?ZHANG Xiuqin

    Department of Respiration， the First Affiliated Hospital of Soochow University， Suzhou? ?215000， China

    [Abstract] Bronchial asthma(asthma) is a very common chronic respiratory disease， and its prevalence is increasing year by year around the world. Although severe asthma accounts for only 5%-10% of all asthma， the large population base of patients with severe asthma in China is huge， and the proportion and cannot be underestimated. The serious impacts of severe asthma on the health status of patients and the resulting heavy disease burden should arouse the attention of clinicians and decision makers. In recent years， individualized targeted therapy based on biologics has developed extremely rapidly， and biologically targeted therapy has improved the quality of life of patients and brought new benefits to patients with severe asthma. Through retrospecting the latest guidelines and research progress at home and abroad in recent years ......