[摘要] 目的探讨基于多层螺旋CT测量的细胞外容积分数(extracellular volume fraction，fECV)评估胰腺导管腺癌淋巴结转移的诊断效能。方法 回顾性收集2018年3月至2023年3月于嘉兴市第一医院被确诊为胰腺导管腺癌的74例患者的基本资料，所有患者均行多层螺旋CT增强检查，检查前均采集红细胞比容，扫描后测量病灶的平扫、门脉期、平衡期及相同层面腹主动脉CT值，计算fECV。以术后病理结果为金标准，利用受试者操作特征曲线分析fECV术前诊断胰腺导管腺癌淋巴结转移的效能。结果淋巴结转移阳性组33例，阴性组41例。淋巴结转移阳性组与阴性组的门脉期fECV比较，差异无统计学意义(=0.80，>0.05)。淋巴结转移阳性组与阴性组的平衡期fECV比较，差异有统计学意义(=2.84，<0.001)。门脉期及延迟期fECV对淋巴结转移的曲线下面积分别为0.517、0.870。结论 基于多层螺旋CT测量的平衡期fECV分数可评估胰腺导管腺癌淋巴结转移。

    [关键词] 胰腺导管腺癌；CT值；细胞外容积分数；淋巴结转移

    [中图分类号] R445.3[文献标识码] A [DOI] 10.3969/j.issn.1673-9701.2024.26.009

    Assessment of lymph node metastasis in pancreatic ductal adenocarcinoma using extracellular volume fraction

    Department of Radiology， the First Hospital of Jiaxing， Jiaxing 314000， Zhejiang， China

    [Abstract]ObjectiveTo assess the diagnostic efficacy of extracellular volume fraction(fECV) based on multi-slice spiral CT in evaluating lymph node metastasis of pancreatic ductal adenocarcinoma.MethodsA total of 74 patients diagnosed as pancreatic ductal adenocarcinoma from March 2018 to March 2023 in the First Hospitalof Jiaxing were retrospectively collected. All patients underwent enhanced multi-slice spiral CT examination.Hematocrit was collected before examination.CT values at the plain phase ......