[摘要] 目的 探讨结直肠癌肝转移同期手术中肝脏术区感染(surgical site infection，SSI)的危险因素。方法 回顾性分析2020年7月至2024年6月于苏州大学附属第一医院胃肠外科行结直肠癌肝转移同期手术的64例患者的临床资料。根据术后是否发生肝脏SSI将患者分为感染组(n=11)和非感染组(n=53)。收集患者的临床资料，采用多因素Logistic回归模型分析影响SSI的独立危险因素。结果 两组患者接受新辅助治疗比例(P=0.017)、手术顺序(P=0.027)、肝脏切除方式(P=0.025)、手术时间(P=0.002)及肝脏切除大小(P=0.029)比较差异均有统计学意义。多因素Logistic回归分析结果显示手术顺序是SSI的独立危险因素(P=0.044)。结论 手术顺序是结直肠癌肝转移同期手术后SSI的独立危险因素，肠优先切除的患者术后SSI风险更高。合理选择手术顺序，优化手术流程，有助于降低术后感染的发生率，改善患者短期预后。

    [关键词] 结直肠癌肝转移；同期手术；术区感染；手术顺序

    [中图分类号] R735.3" """"[文献标识码] A """""[DOI] 10.3969/j.issn.1673-9701.2025.04.013

    [Abstract] ObjectiveTo investigate the risk factors for surgical site infection (SSI) after synchronous resection for colorectal cancer liver metastasis. Methods The clinical data of 64 patients who underwent synchronous resection for colorectal cancer liver metastasis in the Department of Gastrointestinal Surgery of the First Affiliated Hospital of Soochow University from July 2020 to June 2024 were retrospectively analyzed. Patients were divided into infected group (n=11) and non-infected group (n=53) according to whether postoperative hepatic SSI occurred. Clinical data were collected and multivariate Logistic regression models were used to analyze independent risk factors for SSI. ResultsThere were significant differences in the proportion of patients receiving neoadjuvant therapy (P=0.017) ......