Determination of 30 Pesticide Residues in Spices by QuEChERS Combined with Gas Chromatography-Tandem Mass Spectrometry

    ZHANG Jie， YAN Jun， ZHAO Bo，PENG Tao， WANG Xingzhi*

    (Lanzhou Institute ofFood and Drug Inspection and Testing， Key Laboratory of Pesticide and Veterinary Drug

    Monitoring， State Administration for Market Regulation， Gansu Engineering Research Center for Monitoring Exogenous Harmful Residues in Traditional Chinese Medicines，Lanzhou 73oo50， China)

    Abstract： Objective： To establish a gas chromatography-tandem mass spectrometry method for the determination of 30 common pesticide residues in spices. Method： Samples were hydrated for 30min ， extracted with 1% acetic acid-acetonitrile via vortex-assisted extraction， and purified using a QuEChERS cleanup tube containing 150mg anhydrous magnesium sulfate and 50mg primary secondary amine. Compound separation was achieved usinga DB-5MS capillary column (30m×0.25mm ， 0.25μm ，andmass spectrometry detection wasperformed in multiple reaction monitoring mode with matrix-matched calibration standards to corrct for matrix efects. Result： The 30 pesticides exhibited good linearity within the concentration range of 0～200ng?mL^-1 . The method's limits of detection ......