王净净教授中西医结合治疗小儿癫痫临床经验(1)
〔摘要〕 小儿癫痫为临床常见的儿科疾病,王净净教授对其研究多年并提出“毒邪致痫”“痰瘀毒互结”等学说,强调分期而治、标本同治、病证结合辨证施治,坚持儿童用药“能中不西”的原则,对于“海马波谱”异常的患儿适当加入补肾类中药,并创立了“愈痫灵方”经验方,形成系统、成熟且独特有效的中西医结合诊疗方法,值得临床推广借鉴。
〔关键词〕 小儿癫痫;健脾固肾;解毒定惊;中西医结合;王净净
〔中图分类号〕R249;R277.7 〔文献标志码〕B 〔文章编号〕doi:10.3969/j.issn.1674-070X.2020.04.020
WANG Jingjing's Clinical Experience in the Treatment of Pediatric Epilepsy with
Integrated Traditional Chinese and Western Medicine
JI Yadong1, WANG Jingjing2*, SHI Xuehui1, LI Zhixiong2
(1. The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410005, China;
2. Hunan University of Chinese Medicine, Changsha, Hunan 410208, China)
〔Abstract〕 Epilepsy in children is a common pediatric disease in clinical practice. Aftery ears of study, professor WANG Jingjing put forward the theories of "toxin and pathogen causing epilepsy" and "interming led phlegm, blood stasis, and toxin". He emphasized the principle of treating by stages, treating both symptoms and root causes, combiningdisease and syndromes with syndrome differentiation and treatment. He adhered to the medication principle of "TCM first" for children, and put forward the appropriate addition of tonifying kidney herbs for children with abnormal "Hippocampal spectrum", and created the empirical formula of "Yuxianling Recipe", forming a systematic, mature and unique and effective method of integrated traditional Chinese and western medicine, which is worthy of clinical popularization and reference.
〔Keywords〕 pediatric epilepsy; fortifying the spleen and kidney; detoxifying and arresting convulsion; integrated traditional Chinese and western medicine; WANG Jingjing
小兒癫痫[1]是指发生于18周岁以下,以反复发作的肌肉抽搐症状和意识障碍现象为主要特点的一种儿科常见疾病。西医学根据癫痫的发病年龄常称之为儿童癫痫[2],婴幼儿期即可起病,多发生在学龄期间,发作类型多种多样,患儿多伴不同程度的心理、认知等功能障碍,影响生活质量[3]。王净净教授系全国第五批名老中医药专家学术经验继承工作指导老师,国家中医药管理局全国名老中医药专家传承工作室指导专家。王教授出身于医学世家,从医40余年,潜心研究,对小儿癫痫的诊治有独到的心得。余有幸跟随王教授学习三年,现将王教授运用中西医结合方法治疗小儿癫痫的经验总结如下。
1 病因病机
西医学认为癫痫是多种原因引起的脑内神经元群反复发作性过度放电引发的突发性、暂时性脑功能失常,临床表现十分复杂[4]。中医学认为,小儿癫痫的发病可归纳为“先天”与“后天”两方面。先天则多与胎养相关,如 《素问·奇病论》中“帝曰:人生而有病巅疾者,……此得之在母腹中时,其母有所大惊,气上而不下,精气并居,故令子发巅疾也”,认为胎儿在母腹中时,母体受惊致气上而不下,使气机逆乱,影响胎元发为癫痫;又如《诸病源侯论》:“小所以少病痫者,其母怀娠,时时劳役,运动骨血,则气强胎养盛故也。若侍御多,血气微,胎养弱,则儿软脆易伤,故多病痫。”认为胎养期间若母体过劳则使养育胎儿之血气微弱,使胎儿软脆易伤而多发癫痫。另外先天因素还可能与父母之禀赋相关,如周之干《慎斋遗书·羊癫风》云:“羊癫风,系先天之元阴不足,以致肝邪克土伤心故也”,陈复正《幼幼集成·痫证》:“夫病至于痫,非禀于先天不足,即由于攻伐过伤。”皆说明小儿易患癫痫可能与父母之禀赋虚弱密切相关[5]。小儿癫痫之后天因素则与“风、痰、瘀、虚、惊、毒”相关,或外风阳邪,炎上犯头而发痫;或肝肾阴虚,风动于内而发痫;或突受惊吓,气机逆乱而发痫;或脾胃虚弱,气机升降失调而聚湿生痰,痰阻于络而发痫;或颅脑损伤,血络受损生瘀,瘀阻脑络而发痫。此外,王净净教授还提出“毒邪致痫”学说,认为小儿癫痫的发生与“毒”邪相关。毒邪致痫有内外毒之分:“外毒”包括物理与化学因素毒物、寄生虫毒、药物聚毒、湿热疫毒。“内毒”则包括痰瘀内阻、血败脑腐、气机不利酿为毒;风火逆乱、灼伤脉络、升降失宜酿为毒;禀赋不足、脾运不健、湿浊内聚化而为毒;胎产不当、胞元受损、形败难救酝酿为毒[6]。, 百拇医药(计亚东 王净净 石学慧 李智雄)
〔关键词〕 小儿癫痫;健脾固肾;解毒定惊;中西医结合;王净净
〔中图分类号〕R249;R277.7 〔文献标志码〕B 〔文章编号〕doi:10.3969/j.issn.1674-070X.2020.04.020
WANG Jingjing's Clinical Experience in the Treatment of Pediatric Epilepsy with
Integrated Traditional Chinese and Western Medicine
JI Yadong1, WANG Jingjing2*, SHI Xuehui1, LI Zhixiong2
(1. The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410005, China;
2. Hunan University of Chinese Medicine, Changsha, Hunan 410208, China)
〔Abstract〕 Epilepsy in children is a common pediatric disease in clinical practice. Aftery ears of study, professor WANG Jingjing put forward the theories of "toxin and pathogen causing epilepsy" and "interming led phlegm, blood stasis, and toxin". He emphasized the principle of treating by stages, treating both symptoms and root causes, combiningdisease and syndromes with syndrome differentiation and treatment. He adhered to the medication principle of "TCM first" for children, and put forward the appropriate addition of tonifying kidney herbs for children with abnormal "Hippocampal spectrum", and created the empirical formula of "Yuxianling Recipe", forming a systematic, mature and unique and effective method of integrated traditional Chinese and western medicine, which is worthy of clinical popularization and reference.
〔Keywords〕 pediatric epilepsy; fortifying the spleen and kidney; detoxifying and arresting convulsion; integrated traditional Chinese and western medicine; WANG Jingjing
小兒癫痫[1]是指发生于18周岁以下,以反复发作的肌肉抽搐症状和意识障碍现象为主要特点的一种儿科常见疾病。西医学根据癫痫的发病年龄常称之为儿童癫痫[2],婴幼儿期即可起病,多发生在学龄期间,发作类型多种多样,患儿多伴不同程度的心理、认知等功能障碍,影响生活质量[3]。王净净教授系全国第五批名老中医药专家学术经验继承工作指导老师,国家中医药管理局全国名老中医药专家传承工作室指导专家。王教授出身于医学世家,从医40余年,潜心研究,对小儿癫痫的诊治有独到的心得。余有幸跟随王教授学习三年,现将王教授运用中西医结合方法治疗小儿癫痫的经验总结如下。
1 病因病机
西医学认为癫痫是多种原因引起的脑内神经元群反复发作性过度放电引发的突发性、暂时性脑功能失常,临床表现十分复杂[4]。中医学认为,小儿癫痫的发病可归纳为“先天”与“后天”两方面。先天则多与胎养相关,如 《素问·奇病论》中“帝曰:人生而有病巅疾者,……此得之在母腹中时,其母有所大惊,气上而不下,精气并居,故令子发巅疾也”,认为胎儿在母腹中时,母体受惊致气上而不下,使气机逆乱,影响胎元发为癫痫;又如《诸病源侯论》:“小所以少病痫者,其母怀娠,时时劳役,运动骨血,则气强胎养盛故也。若侍御多,血气微,胎养弱,则儿软脆易伤,故多病痫。”认为胎养期间若母体过劳则使养育胎儿之血气微弱,使胎儿软脆易伤而多发癫痫。另外先天因素还可能与父母之禀赋相关,如周之干《慎斋遗书·羊癫风》云:“羊癫风,系先天之元阴不足,以致肝邪克土伤心故也”,陈复正《幼幼集成·痫证》:“夫病至于痫,非禀于先天不足,即由于攻伐过伤。”皆说明小儿易患癫痫可能与父母之禀赋虚弱密切相关[5]。小儿癫痫之后天因素则与“风、痰、瘀、虚、惊、毒”相关,或外风阳邪,炎上犯头而发痫;或肝肾阴虚,风动于内而发痫;或突受惊吓,气机逆乱而发痫;或脾胃虚弱,气机升降失调而聚湿生痰,痰阻于络而发痫;或颅脑损伤,血络受损生瘀,瘀阻脑络而发痫。此外,王净净教授还提出“毒邪致痫”学说,认为小儿癫痫的发生与“毒”邪相关。毒邪致痫有内外毒之分:“外毒”包括物理与化学因素毒物、寄生虫毒、药物聚毒、湿热疫毒。“内毒”则包括痰瘀内阻、血败脑腐、气机不利酿为毒;风火逆乱、灼伤脉络、升降失宜酿为毒;禀赋不足、脾运不健、湿浊内聚化而为毒;胎产不当、胞元受损、形败难救酝酿为毒[6]。, 百拇医药(计亚东 王净净 石学慧 李智雄)
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