蒋宁兰 羊羡 陈邦第 谢汶芳

    〔摘要〕 目的 觀察润肤止痒洗剂联合卡泊三醇软膏治疗血虚风燥型寻常型银屑病静止期的临床疗效及安全性。方法 将血虚风燥型寻常型银屑病静止期患者90例按随机数字表法分为联合组、中药组及西药组，每组30例。联合组予以润肤止痒洗剂外洗联合卡泊三醇软膏外搽治疗，中药组予以润肤止痒洗剂外洗治疗，西药组予以卡泊三醇软膏外搽治疗。疗程8周。观察3组治疗前后银屑病皮损程度评分、瘙痒程度评分及不良反应，以判定临床疗效及安全性。结果 治疗后3组患者皮损面积、红斑、浸润、鳞屑评分及PASI总评分、瘙痒程度评分均较治疗前显著下降(P0.05)。联合组的临床疗效优于中药组、西药组(P0.05)。结论 润肤止痒洗剂联合卡泊三醇软膏治疗血虚风燥型寻常型银屑病静止期疗效确切，优于单用卡泊三醇软膏和单用润肤止痒洗剂的疗效，且用药安全可靠。

    〔关键词〕 寻常型银屑病;血虚风燥证;润肤止痒洗剂;卡泊三醇软膏;临床研究

    〔中图分类号〕R275.9? ? ? ?〔文献标志码〕B? ? ? ?〔文章编号〕doi：10.3969/j.issn.1674-070X.2021.01.025

    〔Abstract〕? Objective To observe the clinical efficacy and safety of Runfu Zhiyang lotion combined with calcipotriol ointment in the treatment of resting stage of psoriasis vulgaris with blood deficiency and wind dryness type. Methods 90 patients with psoriasis vulgaris with blood deficiency and wind dryness type were randomly divided into the combined group ......