晏显妮 江其龙 刘小斌

    〔摘要〕 脊髓延髓性肌萎缩是一种遗传性位于脑干和脊髓的运动神经元神经退行性疾病，为临床罕见疑难病症，需要依靠基因检测确诊，西医目前缺乏特异性治疗方法。刘小斌教授认为本病归属于中医学“痿证”范畴，病机为“禀赋残缺，胎元不足”“脾胃虚损，肝肾亏虚”。刘教授临床治疗本病多以黄芪、五指毛桃、鹿角霜、紫河车及其他补益之药“调理脾胃，培补肝肾，充盈气血”，注重药食同调，灸药结合，中西医并用;将其中医证型分为脾胃气虚证和脾肾亏虚证，疾病早期以补中益气汤为基础方加减治疗，病至后期，以补中益气汤合地黄饮子加减。

    〔关键词〕 脊髓延髓性肌萎缩;补中益气汤;临床经验;刘小斌;禀赋

    〔中图分类号〕R277.7? ? ? ?〔文献标志码〕B? ? ? ? 〔文章编号〕doi：10.3969/j.issn.1674-070X.2021.10.026

    Professor Liu Xiaobin's Experience in Treating Spinal and Bulbar Muscular Atrophy

    YAN Xianni1， JIANG Qilong1， LIU Xiaobin2*

    (1. The First Affiliated Hospital of Guangzhou University of Chinese Medicine， Guangzhou， Guangdong 510405， China;

    2. Deng Tietao Institute of Guangzhou University of Chinese Medicine， Guangzhou， Guangdong 510405， China)

    〔Abstract〕 Spinal and bulbar muscular atrophy is a hereditary motor neuron neurodegenerative disease located in the brainstem and spinal cord， which is a rare and intractable diseases who depending on genetic testing to diagnose， western medicine lacks specific treatment method at present. Professor Liu Xiaobin thinks that the disease belongs to the category of "flaccidity syndrome” in traditional Chinese medicine (TCM) ......