〔摘要〕 慢加急性肝衰竭“毒浊致病”学说是毛德文教授团队在急性肝衰竭“毒邪致病”学说基础上提炼而来。本文详细介绍慢加急性肝衰竭“毒浊致病”学说的形成、科学内涵及其对中医临床实践的指导意义，充分阐述慢加急性肝衰竭“毒浊致病”学说的科学性及其代表方解毒化瘀Ⅱ方治疗慢加急性肝衰竭的可行性及确切疗效。

    〔关键词〕 慢加急性肝衰竭；毒浊致病；解毒化瘀Ⅱ方；医案举隅；毛德文

    〔中图分类号〕R256.4" " " " "〔文献标志码〕A" " " " " 〔文章编号〕doi：10.3969/j.issn.1674-070X.2024.07.022

    Scientific connotation of \"toxic turbidity causing disease\" theory in acute-on-chronic liver failure and the clinical application of its representative formula， Jiedu Huayu Formula Ⅱ

    FENG Peipei1， SHI Qinglan2*， MAO Dewen2， YANG Min1， YANG Fan1， TAO Xiangjun1，

    HUANG Qianming1， ZHAO Qingqing1， PAN Qiuhe1

    1. Guangxi University of Chinese Medicine， Nanning， Guangxi 530000， China; 2. The First Hospital of Guangxi

    University of Chinese Medicine， Nanning， Guangxi 530000， China

    〔Abstract〕 The theory of \"toxic turbidity causing disease\" in acute-on-chronic liver failure (ACLF) is refined by Professor MAO Dewen's team based on the theory of \"toxic pathogen causing disease\" in acute liver failure. This paper provides a detailed introduction to the formation and scientific connotation of the \"toxic turbidity causing disease\" theory in ACLF ......