〔摘要〕 在心肌缺血损伤的病理过程中，线粒体能量代谢障碍是心肌细胞凋亡或坏死的关键因素。因此，靶向线粒体的干预策略对心肌缺血损伤的防治具有现实意义。“阳化气，阴成形”理论是阴阳含义的具体化，可以概括现代医学有关心肌缺血损伤的病理演变过程。线粒体功能障碍-阳化气不及-气化障碍是疾病病理过程的基础，阴成形太过-心肌能量代谢异常-有形实邪积聚是疾病病理过程的关键。谨遵病机特点，阐明扶阳补虚、抑阴祛邪的中医治疗原则对心肌缺血线粒体能量代谢机制的指导作用，以期为后续临床治疗和基础研究提供更多思路。

    〔关键词〕 心肌缺血损伤;线粒体功能;心肌能量代谢;阳化气，阴成形

    〔中图分类号〕R256.2" " " " "〔文献标志码〕A" " " " " 〔文章编号〕doi：10.3969/j.issn.1674-070X.2024.08.021

    Effects of mitochondrial energy metabolism disorders on myocardial ischemic injury based on the theory of \"yang transforming into

    qi and yin constituting form\"

    GUO Yanyan1，2， YUAN Xixi1， ZHAO Mingfen1，2*

    1. The Fourth Clinical Medical College， Xinjiang Medical University， Urumqi， Xinjiang 830000， China; 2. Cadre Office，

    Chinese Medicine Hospital of Xinjiang Medical University， Urumqi， Xinjiang 830099， China

    〔Abstract〕 During the pathological process of myocardial ischemic injury， and mitochondrial energy metabolism disorders are a key factor in myocardial cell apoptosis and necrosis. Therefore， the intervention strategy targeting mitochondria has practical significance for the prevention and treatment of myocardial ischemic injury. The theory of \"yang transforming into qi and yin constituting form\" is a concrete interpretation of the meaning of yin and yang ......