〔摘要〕 结直肠癌是常见的消化系统恶性肿瘤，可归属于中医学“积聚”“脏毒”“肠风”等范畴。在病因上，结直肠癌发病可因外感所致，亦可因内伤引发；病机上，其特点为正虚伏毒，即以正气亏虚为本，以痰饮、湿浊、血瘀凝聚为标；病势上，其特点为隐伏、暴戾、暗耗、迁延不愈。通过探究伏毒理论，认为其与结直肠癌在病因、病机、病势特点上有较多相似之处。风药具有宣散透邪、疏肝行气、胜湿行散、活血消癥、搜风通络、扶正透散等功效，为结直肠癌的防治提供了新的研究思路与方法。

    〔关键词〕 伏毒；风药；积聚；结直肠癌；扶正祛邪

    〔中图分类号〕R273" " " " "〔文献标志码〕A" " " " " 〔文章编号〕doi：10.3969/j.issn.1674-070X.2024.11.026

    Application of wind medicines in treating colorectal cancer

    based on the latent toxin theory

    LI Zhonglin1， LI Yu1， JIA Xiaowei1， TANG Yushi1， LI Cheng1，2*

    1. School of Traditional Chinese Medicine， Tianjin University of Traditional Chinese Medicine， Tianjin 301617， China;

    2. Tianjin Key Laboratory of Innovation and Transformation for Modern Chinese Medicine Theory， Tianjin 301617， China

    〔Abstract〕 Colorectal cancer is a common malignant tumor of the digestive system， which can be classified into the categories of \"abdominal masses\"， \"anal abscess\"， and \"intestinal wind (bloody stools)\" in Chinese medicine. It can be caused by either exogenous pathogenic factors or endogenous ones. The characteristics of its pathogenesis can be summarized as latent toxins with a deficiency of healthy qi ......