〔摘要〕 以“痰瘀同治”理论为基础并结合临床验案，探析慢性阻塞性肺疾病急性加重(acute exacerbation of chronic obstructive pulmonary disease， AECOPD)高凝状态的病机与治则，认为“因痰致瘀，痰瘀互结”是AECOPD高凝状态的病机关键，即痰是其始动因素，瘀是其继发产物，是因痰致瘀而后又痰瘀互结的病理改变。治疗上既要重视痰之本，也要兼顾血瘀，以活血辅助祛痰，以化痰达祛瘀之功。如此“痰瘀同治”可有效缓解患者临床症状，预防血栓性疾病的发生。

    〔关键词〕 慢性阻塞性肺疾病急性加重;高凝状态;痰瘀同治;活血；化痰；祛瘀；验案

    〔中图分类号〕R256" " " " "〔文献标志码〕A" " " " " 〔文章编号〕doi：10.3969/j.issn.1674-070X.2024.11.029

    Differentiation and treatment of hypercoagulable state in acute exacerbation of chronic obstructive pulmonary disease based on the theory of

    \"simultaneous treatment of phlegm and blood stasis\"

    XU Mengjiao， WANG Wei， LIU Huimei， WANG Bin， GAO Feng*

    Wangjing Hospital of China Academy of Chinese Medical Sciences， Beijing 100000， China

    〔Abstract〕 Based on the theory of \"simultaneous treatment of phlegm and blood stasis\"， this paper explores the pathogenesis and treatment principles of hypercoagulable state in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) combined with a verified clinical medical record. It is proposed that \"the formation of phlegm leading to blood stasis ......