〔摘要〕 肿瘤心脏病学是近年来出现的新兴学科，指肿瘤或抗肿瘤治疗手段引起的心血管病变，严重影响肿瘤患者的生存期及预后。目前，肿瘤心脏病治疗多遵循相应心血管病的临床指南，治疗方案亟待完善。基于“瘀毒”理论，根据肿瘤心脏病患者血液高凝状态、炎症反应活跃等特点，提出肿瘤心脏病患者“虚为本，瘀为常，毒为变”的中医病机。“虚瘀毒”三者互为因果，患者久病体虚，气血壅阻脉中，瘀血内蕴，化生热毒，瘀毒胶结，阻碍气血运行，体虚更甚。益气活血解毒中药可多途径、多靶点抑制炎症反应，改善凝血功能，保护血管内皮，从而改善心脏功能。“益气活血解毒”被提出为贯穿肿瘤心脏病全病程的治疗总则，以期为肿瘤心脏病的临床诊治提供新思路。

    〔关键词〕 “瘀毒”理论;“虚瘀毒”;肿瘤心脏病;益气活血解毒;诊治思路

    〔中图分类号〕R259" " " " "〔文献标志码〕A" " " " " 〔文章编号〕doi：10.3969/j.issn.1674-070X.2024.12.025

    Treatment of cardio-oncologic diseases from the perspective of"\"deficiency， blood stasis， and toxicity\"

    WANG Xinyue1， LIU Longtao2， WU Min1*

    1. Guang'anmen Hospital， China Academy of Chinese Medical Sciences， Beijing 100053， China;

    2. Xiyuan Hospital， China Academy of Chinese Medical Sciences， Beijing 100091， China

    〔Abstract〕 Cardio-oncology， as an emerging discipline in recent years， involves the cardiovascular lesions caused by tumors or anti-tumor therapies， which seriously affect the survival and prognosis of tumor patients. Currently， treatment for cardio-oncologic diseases mostly follows the clinical guidelines for the corresponding cardiovascular diseases ......