本文引用：，.从“脾失散精、毒邪内生”理论与线粒体自噬介导铁死亡探讨溃疡性结肠炎病机[J].湖南中医药大学学报，2025，45(4)：748-752.

    [关键词]溃疡性结肠炎；脾失散精；毒邪内生；线粒体自噬；铁死亡；氧化应激 [中图分类号]R25 [文献标志码]A [文章编号]doi：10.3969/j.issn.1674-070X.2025.04.025

    [Abstract] Chinese medicine posits that \"spleen deficiency leading to dysfunctionof esence distributionandendogenous toxicpathogens\"isthepathogenesisofhonicareaichisalogoustolerativecolitis(UCcusedbymitopagiated feroptosis.BasedontheTCMtheoryof\"analogyandimagery\"，\"spleendeficiencyleadingtodysfunctionofessencedistribution\" corespondstocelularenergydeficiencyesultingfrommitophagy，while\"endogenoustoxicpathogens\"areakintoinflammatory reactiontrigeredbyferoptosis.Therefore，thispaperaims toexplorethemechanismofactionofTCMinregulatingmitophagymediatedferroptosisforthetreatmentofUC，basedonthetheoryof\"spleen deficiencyleading todysfunctionof essence distributionandendogenoustoxicpathogens\".Furthermore，ithasprovidedanin-depthanalysisoftheinterplayamong mitophagy ferroptosis，and UC，offering areliable basisand noveltherapeutic insights forthe modernizationof TCMresearch.

    [Keywords]ulcerativecolitis；spleendeficiencyleadingtodysfunctionofesencedistribution;endogenoustoxicpathogens; mitophagy； ferroptosis; oxidative stress ......