本文引用：，.教授从“伏毒致痹\"探析奥沙利铂所致急性周围神经毒性[J].湖南中医药大学学报，2025，45(5)：910-915.

    [关键词]奥沙利铂；周围神经病变；神经毒性；伏毒；温阳通络散；名医经验 [中图分类号]R249 [文献标志码]A [文章编号]doi：10.3969/j.issn.1674-070X.2025.05.018

    [Abstract]Oxaliplatinisathird-generation platinum drug，which is widelyusedindigestivetracttumors，anditsadverse reactionsaremostcommoninoxaliplatin-inducedperipheralneurotoxicity(OIPN)，whichisclasifiedintotwotypes：acuteand chronic.cuteoxaliplatin-inducedperipheralneurotoxicity (AOIPN)isatransientneurotoxicitysymptomoccuring within24-48h afteroxaliplatininfusionhichisdominatedbysnsoryabnomalitiesthatafectspatientsqualtyoflifeandinsverecases， forcingthemtochangetheirtreatmentregimenandafectingsurvival.ProfesorLIULikunbelievesthathidentoxicityisthe causative factorofOP，whichisharacterizedbyimpedientblockingvesselsandcolateralsandstrongconcealmentdiis treatedbywarmingcoldanddampness，expelingtoxinsandremoving bloodstasis，andthecombinationofexternalwashingwith theself-draftedWenyang TongluoPowderhasaremarkabletherapeuticefectThispaperdiscussesthetreatmentofAOIPfrom thetheoryof\"atenttoxicitycausingimpediment\" ......