[关键词]免疫性血小板减少症；调肝益血汤；血小板生成素；造血干细胞；巨核细胞 [中图分类号]R285.5 [文献标志码]A [文章编号]doi：10.3969/j.issn.1674-070X.2025.06.003

    Effects of Tiaogan Yixue Decoction on the differentiation of CD34⁺ hematopoietic stem cells into megakaryocytes in IT rats by regulating the secretion of TPO in hepatocytes

    NIE Tian'， YI Qinl*， XU Ronghua’， YANG Lin'， ZHOU Xinxin'，HAO Jingquan'，LI Qinghu2* 1.The First Hospital of Hunan Universityof Chinese Medicine，Changsha Hunan 41oo07，China;2.The Second Hospital of Hunan University of Chinese Medicine， Changsha， Hunan 41ooo5，China

    [Abstract]ObjectiveToinvestigatetheeffectsof Tiaogan Yixue Decoction (TGYXD)onthediferentiationofbonemarrow (204 CD34⁺ hematopoieticstemcells intomegakaryocytesinimmune thrombocytopenia(I)ratsbypromoting thrombopoietin (TPO) productioninhepatocytes.MethodsSixtySDratswerestratifiedbybodyweightintoablankgroup(1Orats，receivinganequal volumeofpurifiedwater)andamodelinggroup(5Orats.ThemodelinggroupestablishedtheITatmodelusingtheserummethodof rabbitanti-SDrats.Aftersucesfulmodeling，theyweredividedintoamodelgroup(equalvolumeofpurifiedwater) ......