胆管癌患者血清CA125\CA19-9和CA50的水平变化及临床意义(1)
胆管癌患者血清CA125\CA19-9和CA50的水平变化及临床意义, ,CA125CA19-9CA50胆管癌肿瘤标志物
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【摘要】 目的探讨胆管癌患者血清CA125、CA19-9和CA50的水平变化及临床意义。方法用全自动电化学发光分析仪测定45例胆管癌患者(胆管癌组)及40例健康查体者(对照组)血清CA19-9、CA125及CEA水平。根据试剂厂家提供的参考值计算3种标志物分别以及联合检测诊断胆管癌的敏感性、特异性及准确性。结果诊断胆管癌血清CA19-9、CA50的灵敏度较好(80.00%、91.43%),血清CA125的特异度最好(61.29%),联合检测灵敏度为88.64%,其误诊率下降至5%。结论联合检测肿瘤标志物对胆管癌的诊断具有协同作用,准确度增加,误诊率降低。
【关键词】 CA125CA19-9CA50胆管癌肿瘤标志物
【中图分类号】 R446【文献标识码】 A【文章编号】 1674-0742(2011)05(a)-0011-02
Level variation of CA125、CA19-9 and CA50 in cholangiocarcinom and Its clinical significance
【Abstract】 Objectiveto explore the Level variation of CA125、CA19-9 and CA50 in cholangiocarcinom and its clinical significance.MethodsRadioimmunoassay and immunoradiometricassay were adopted to detect CA125、CA19-9 and CA50 in venous serum of 40 patients with cholangiocarcinoma and 40 healthy cases;According to the control value applied by company,Sensitivity, specificity and accuracy were detected ......
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