与川崎病发病及冠状动脉损伤相关的易感基因(1)
[摘要] 川崎病(KD)是婴幼儿时期的急性血管炎,已成为发达国家儿童获得性心脏病最常见的原因,可导致冠状动脉病变而出现心肌缺血、梗死甚至死亡。尽管近50多年的研究,然而其病因和发病机制尚不完全清楚。目前关于KD的研究多集中于遗传易感性和免疫发病机理。好发于亚裔人群和一级亲属患病率高表明遗传因素与KD的易感性有关。本文概述了与川崎病发病及冠状动脉损伤相关基因的最新研究进展。
[关键词] 川崎病;易感基因;冠状动脉损伤
[中图分类号] R725.4 [文献标识码] A [文章编号] 1674-0742(2016)06(a)-0197-02
[Abstract] Kawasaki disease (KD) is an acute vasculitis of infancy and childhood that has become the leading cause of acquired heart disease in children in the developed world ......
您现在查看是摘要页,全文长 3895 字符。
[关键词] 川崎病;易感基因;冠状动脉损伤
[中图分类号] R725.4 [文献标识码] A [文章编号] 1674-0742(2016)06(a)-0197-02
[Abstract] Kawasaki disease (KD) is an acute vasculitis of infancy and childhood that has become the leading cause of acquired heart disease in children in the developed world ......
您现在查看是摘要页,全文长 3895 字符。