血清孕酮、β—HCG联合检测在早期先兆流产中的诊断价值(1)
DOI：10.16662/j.cnki.1674-0742.2017.23.110
[摘要] 目的 讨论血清孕酮、β-HCG联合检测在早期先兆流产中的诊断价值。方法 病例均方便选自2015年6月—2016年6月期间，实验组选取该院救治的先兆流产的患者32例，对照组选取在该院救治的流产的患者44例，健康对照组选取健康的志愿者30名，3组均实行血清孕酮、β-HCG的检测，对3组的检测结果实行比较。结果 对照组患者的血清孕酮、β-HCG分别为(11.5±6.8)ng/mL、(4 531.1±436.3)mIU/mL检测低于健康对照组(25.9±8.7)ng/mL、(18 325.2±551.3)mIU/mL，实验组(16.6±6.5)ng/mL、(13 452.5±441.7)mIU/mL，差异有统计学意义(P<0.05)。血清孕酮，β-HCG以及血清孕酮联合β-HCG的特异性为86.00%，100.00%，91.00%。结论 可以使用血清孕酮、β-HCG联合检测早期的先兆流产，从而提高对患者出现先兆流产的预测，具有重要的临床价值。
[关键词] 血清孕酮；β-HCG；早期先兆流产
[中图分类号] R714 [文献标识码] A [文章编号] 1674-0742(2017)08(b)-0110-03
Diagnostic Value of Combined Detection of Serum Progesterone and β-HCG in Early Threatened Abortion
LI Yan
Department of Obstetrics and Gynecology， Pu’er People’s Hospital， Pu’er， Yunnan Province， 665000 China
[Abstracts] Objective This paper tries to discuss the combined detection of serum progesterone and β-HCG in the early diagnosis of threatened abortion. Methods 23 patients with threatened abortion in this hospital from June 2015 to June 2016 were convenient selected as the experimental group. 44 cases of abortion cured in this hospital were selected as the control group， and 30 healthy volunteers were selected as the healthy control group. The serum progesterone and β-HCG were detected in the three groups. The results of the three groups were compared. Results Serum progesterone and β-HCG were(11.5±6.8) ng/mL and(4531.1±436.3) mIU/mL in the control group， lower than that in the healthy control group of (25.9±8.7)ng/mL (18 325.2±551.3)mIU/mL， and the experimental group of (16.6±6.5)ng/mL and (13 452.5±441.7)mIU/mL， the differences were statistically significant(P<0.05). The specificity of serum progesterone， β-HCG and serum progesterone combined with β-HCG were 86.00%， 100.00% and 91.00% respectively. Conclusion Serum progesterone and β-HCG can be used to detect early threatened abortion， so as to improve the prediction of threatened abortion in patients， which has important clinical value.
[Key words] Serum progesterone； β-HCG； Early threatened abortion
早期先兆流產是指在孕妇在妊娠12周以前，出现少量的阴道出血的情况，并伴随着阵发性的下腹疼痛或者腰背痛的疾病[1]。早期先兆流产是一种常见的妊娠并发症。在临床上使用超声以及胎心搏动检测不能准确的检测出患者是否出现早期先兆流产[2]。该文中实验组选取该院救治的先兆流产的患者32例，对照组选取在该院救治的流产的患者44例，病例均方便选自2015年6月—2016年6月期间。健康对照组选取健康的志愿者30名，3组均实行血清孕酮、β-HCG的检测，对3组的检测结果实行比较，现报道如下。
1 资料与方法
1.1 一般资料
实验组方便选取该院救治的先兆流产的患者32例，对照组方便选取在该院救治的流产的患者44例，健康对照组选取健康的志愿者30名，3组均实行血清孕酮、β-HCG的检测，对3组的检测结果实行比较。其中，实验组孕妇32例，年龄在20～39岁之间，平均年龄在(28.3±3.5)岁。对照组孕妇44例，年龄在20～40岁之间，平均年龄在(29.2±2.1)岁。健康对照组孕妇30名，年龄在21～41岁之间，平均年龄在(28.4±2.9)岁。排除标准：①孕妇有其他重大疾病，如严重肾衰竭等。②孕妇患有精神类的疾病，不能配合实验实行。③孕妇患有严重的肿瘤的情况。④孕妇不同意进行实验。, 百拇医药(李艳)
[摘要] 目的 讨论血清孕酮、β-HCG联合检测在早期先兆流产中的诊断价值。方法 病例均方便选自2015年6月—2016年6月期间，实验组选取该院救治的先兆流产的患者32例，对照组选取在该院救治的流产的患者44例，健康对照组选取健康的志愿者30名，3组均实行血清孕酮、β-HCG的检测，对3组的检测结果实行比较。结果 对照组患者的血清孕酮、β-HCG分别为(11.5±6.8)ng/mL、(4 531.1±436.3)mIU/mL检测低于健康对照组(25.9±8.7)ng/mL、(18 325.2±551.3)mIU/mL，实验组(16.6±6.5)ng/mL、(13 452.5±441.7)mIU/mL，差异有统计学意义(P<0.05)。血清孕酮，β-HCG以及血清孕酮联合β-HCG的特异性为86.00%，100.00%，91.00%。结论 可以使用血清孕酮、β-HCG联合检测早期的先兆流产，从而提高对患者出现先兆流产的预测，具有重要的临床价值。
[关键词] 血清孕酮；β-HCG；早期先兆流产
[中图分类号] R714 [文献标识码] A [文章编号] 1674-0742(2017)08(b)-0110-03
Diagnostic Value of Combined Detection of Serum Progesterone and β-HCG in Early Threatened Abortion
LI Yan
Department of Obstetrics and Gynecology， Pu’er People’s Hospital， Pu’er， Yunnan Province， 665000 China
[Abstracts] Objective This paper tries to discuss the combined detection of serum progesterone and β-HCG in the early diagnosis of threatened abortion. Methods 23 patients with threatened abortion in this hospital from June 2015 to June 2016 were convenient selected as the experimental group. 44 cases of abortion cured in this hospital were selected as the control group， and 30 healthy volunteers were selected as the healthy control group. The serum progesterone and β-HCG were detected in the three groups. The results of the three groups were compared. Results Serum progesterone and β-HCG were(11.5±6.8) ng/mL and(4531.1±436.3) mIU/mL in the control group， lower than that in the healthy control group of (25.9±8.7)ng/mL (18 325.2±551.3)mIU/mL， and the experimental group of (16.6±6.5)ng/mL and (13 452.5±441.7)mIU/mL， the differences were statistically significant(P<0.05). The specificity of serum progesterone， β-HCG and serum progesterone combined with β-HCG were 86.00%， 100.00% and 91.00% respectively. Conclusion Serum progesterone and β-HCG can be used to detect early threatened abortion， so as to improve the prediction of threatened abortion in patients， which has important clinical value.
[Key words] Serum progesterone； β-HCG； Early threatened abortion
早期先兆流產是指在孕妇在妊娠12周以前，出现少量的阴道出血的情况，并伴随着阵发性的下腹疼痛或者腰背痛的疾病[1]。早期先兆流产是一种常见的妊娠并发症。在临床上使用超声以及胎心搏动检测不能准确的检测出患者是否出现早期先兆流产[2]。该文中实验组选取该院救治的先兆流产的患者32例，对照组选取在该院救治的流产的患者44例，病例均方便选自2015年6月—2016年6月期间。健康对照组选取健康的志愿者30名，3组均实行血清孕酮、β-HCG的检测，对3组的检测结果实行比较，现报道如下。
1 资料与方法
1.1 一般资料
实验组方便选取该院救治的先兆流产的患者32例，对照组方便选取在该院救治的流产的患者44例，健康对照组选取健康的志愿者30名，3组均实行血清孕酮、β-HCG的检测，对3组的检测结果实行比较。其中，实验组孕妇32例，年龄在20～39岁之间，平均年龄在(28.3±3.5)岁。对照组孕妇44例，年龄在20～40岁之间，平均年龄在(29.2±2.1)岁。健康对照组孕妇30名，年龄在21～41岁之间，平均年龄在(28.4±2.9)岁。排除标准：①孕妇有其他重大疾病，如严重肾衰竭等。②孕妇患有精神类的疾病，不能配合实验实行。③孕妇患有严重的肿瘤的情况。④孕妇不同意进行实验。, 百拇医药(李艳)