基层医院小儿社区获得性肺炎抗菌药物的用药情况及疗效调查(1)
DOI:10.16662/j.cnki.1674-0742.2017.25.129
[摘要] 目的 分析基层医院小儿社区获得性肺炎抗菌药物的用药情况及疗效调查。方法 方便选取2015年6月—2016年12月该院诊治的122例小儿社区获得性肺炎患儿进行回顾性分析。结果 在治疗效果方面:治愈率66.39%;显效率28.69%;无效率4.92%。在不良反应方面:服用林可霉素有5例,用青霉素有4例;用阿奇霉素有2例。该次应用最多的就是林可霉素类和头孢菌素类药物。 结论 对小儿社会获得性肺炎患儿运用抗菌药物效果显著,能有效的改善临床症状,降低病痛,对于病情严重可采用两种药物联合治疗,从而达到延长细菌耐药性的情况,提高抗菌效果。但建议临床医师要熟练掌握各个抗菌药物的药理特点、具体不良症状以及病原学诊断等方面情况,能够合理的应用抗菌药物。
[关键词] 社区获得性肺炎;基层医院小儿;抗菌药物
[中图分类号] R725 [文献标识码] A [文章编号] 1674-0742(2017)09(a)-0129-03
Investigation on Drug Use and Curative Effect of Community-acquired Pneumonia Antibiotics in Primary Hospital
ZHENG Zhi-yan
Department of Pediatrics, Nanping Maternal and Child Health Care Hospital, Nanping, Fujian Province, 353000 China
[Abstract] Objective This paper tries to analyze the antimicrobial agents’ usage and efficacy of community acquired pneumonia in children in primary hospitals. Methods A retrospective analysis of 122 children with community-acquired pneumonia from June 2015 to December 2016 in this hospital was carried out. Results As for the curative effect: the curative rate was 66.39%, the effective rate was 28.69%, and the invalid rate was 4.92%. In adverse symptoms: 5 cases were treated with lincomycin, 4 cases with penicillin, and 2 cases with azithromycin. The most widely used were lincomycin and cephalosporins. Conclusion The curative effect of antibacterial drugs on acquired pneumonia children is significant, which can improve their clinical symptoms, reduce the pain. As for those whose illness is severe, the combined medicine care can be adopted so as to extend the bacterial resistance and improve the antibacterial effect. But it is suggested that clinicians should master the pharmacological characteristics, specific adverse symptoms and etiological diagnosis of each antimicrobial agent, and be able to rationally use antibiotics.
[Key words] Community acquired pneumonia; Children in primary hospital; Antimicrobial agents
社区获得性肺炎是一种感染性肺实质炎症,通常是在医院外发生的,但是社区获得性肺炎有潜伏期,多数情况都是患者在潜伏期内住院才发现此疾病的,是临床中比较多见的肺部炎症疾病。社区获得性肺炎的发病机制比较复杂,导致此疾病的主要病菌有流感嗜血杆菌、肺炎球菌、衣原体、他莫杆菌以及军团杆菌等等[1]。对此疾病进行统计分析时发现,社区获得性肺炎有着极高的死亡率,而且位于死亡疾病的前10位。特别是偏于地區、医疗设备不完善的地方发生率是更高。社会获得性肺对我国人民的生命健康产生严重威胁。特别是小儿患者,由于身体各项器官发育不成熟,抵抗能力差,特别容易受到病毒的侵袭,所以,对社区获得性肺炎小儿患者采用积极有效的方法进行治疗有着重要的意义。一般所采用的治疗方法就是给予患者抗菌类药物,例如头孢菌素、林可霉素类等等,但是在应用过程中存在应用抗菌类药物不合理的问题,导致患者机体内的细菌产生耐药性,影响治疗效果。因此,该文针对基层医院2015年6月—2016年12月小儿社区获得性肺炎患儿122例的临床资料进行回顾性分析,探究抗菌药物的用药情况和治疗效果,现报道如下。
1 资料与方法
1.1 一般资料, 百拇医药(郑志燕)
[摘要] 目的 分析基层医院小儿社区获得性肺炎抗菌药物的用药情况及疗效调查。方法 方便选取2015年6月—2016年12月该院诊治的122例小儿社区获得性肺炎患儿进行回顾性分析。结果 在治疗效果方面:治愈率66.39%;显效率28.69%;无效率4.92%。在不良反应方面:服用林可霉素有5例,用青霉素有4例;用阿奇霉素有2例。该次应用最多的就是林可霉素类和头孢菌素类药物。 结论 对小儿社会获得性肺炎患儿运用抗菌药物效果显著,能有效的改善临床症状,降低病痛,对于病情严重可采用两种药物联合治疗,从而达到延长细菌耐药性的情况,提高抗菌效果。但建议临床医师要熟练掌握各个抗菌药物的药理特点、具体不良症状以及病原学诊断等方面情况,能够合理的应用抗菌药物。
[关键词] 社区获得性肺炎;基层医院小儿;抗菌药物
[中图分类号] R725 [文献标识码] A [文章编号] 1674-0742(2017)09(a)-0129-03
Investigation on Drug Use and Curative Effect of Community-acquired Pneumonia Antibiotics in Primary Hospital
ZHENG Zhi-yan
Department of Pediatrics, Nanping Maternal and Child Health Care Hospital, Nanping, Fujian Province, 353000 China
[Abstract] Objective This paper tries to analyze the antimicrobial agents’ usage and efficacy of community acquired pneumonia in children in primary hospitals. Methods A retrospective analysis of 122 children with community-acquired pneumonia from June 2015 to December 2016 in this hospital was carried out. Results As for the curative effect: the curative rate was 66.39%, the effective rate was 28.69%, and the invalid rate was 4.92%. In adverse symptoms: 5 cases were treated with lincomycin, 4 cases with penicillin, and 2 cases with azithromycin. The most widely used were lincomycin and cephalosporins. Conclusion The curative effect of antibacterial drugs on acquired pneumonia children is significant, which can improve their clinical symptoms, reduce the pain. As for those whose illness is severe, the combined medicine care can be adopted so as to extend the bacterial resistance and improve the antibacterial effect. But it is suggested that clinicians should master the pharmacological characteristics, specific adverse symptoms and etiological diagnosis of each antimicrobial agent, and be able to rationally use antibiotics.
[Key words] Community acquired pneumonia; Children in primary hospital; Antimicrobial agents
社区获得性肺炎是一种感染性肺实质炎症,通常是在医院外发生的,但是社区获得性肺炎有潜伏期,多数情况都是患者在潜伏期内住院才发现此疾病的,是临床中比较多见的肺部炎症疾病。社区获得性肺炎的发病机制比较复杂,导致此疾病的主要病菌有流感嗜血杆菌、肺炎球菌、衣原体、他莫杆菌以及军团杆菌等等[1]。对此疾病进行统计分析时发现,社区获得性肺炎有着极高的死亡率,而且位于死亡疾病的前10位。特别是偏于地區、医疗设备不完善的地方发生率是更高。社会获得性肺对我国人民的生命健康产生严重威胁。特别是小儿患者,由于身体各项器官发育不成熟,抵抗能力差,特别容易受到病毒的侵袭,所以,对社区获得性肺炎小儿患者采用积极有效的方法进行治疗有着重要的意义。一般所采用的治疗方法就是给予患者抗菌类药物,例如头孢菌素、林可霉素类等等,但是在应用过程中存在应用抗菌类药物不合理的问题,导致患者机体内的细菌产生耐药性,影响治疗效果。因此,该文针对基层医院2015年6月—2016年12月小儿社区获得性肺炎患儿122例的临床资料进行回顾性分析,探究抗菌药物的用药情况和治疗效果,现报道如下。
1 资料与方法
1.1 一般资料, 百拇医药(郑志燕)