[摘要] 目的 探讨脑钠肽评估慢性阻塞性肺病和慢性肺源性心脏病严重程度的临床价值。方法 方便选取2014年4月—2016年4月该院收治的46例慢性阻塞性肺病急性加重期患者为A组，择取同期该院收治的46例慢性肺源性心脏病代偿期患者为B组、46例慢性肺源性心脏病失代偿期患者为C组。于清晨空腹抽取3组血液样本，以酶联免疫吸附法检测3组血浆脑钠肽水平并进行对比观察。结果 A组脑钠肽(87.2±30.4)ng/L，B组脑钠肽(224.6±71.5)ng/L，C组脑钠肽(438.1±96.7)ng/L，组间比较差异有统计学意义(P<0.05)。结论 慢性阻塞性肺疾病和慢性肺源性心脏病的病理生理过程与脑钠肽存在密切关联，血浆脑钠肽水平可作为判断患者病情严重程度的有效指标为临床诊治及预后评估提供有价值的参考。

    [关键词] 脑钠肽；慢性阻塞性肺病；慢性肺源性心脏病

    [中图分类号] R563 [文献标识码] A [文章编号] 1674-0742(2017)11(c)-0053-03

    [Abstract] Objective This paper tries to investigate the clinical value of brain natriuretic peptide in assessing the severity of chronic obstructive pulmonary disease and chronic pulmonary heart disease. Methods 46 patients with acute exacerbation of chronic obstructive pulmonary disease from April 2014 to April 2016 were conveniently enrolled in group A. 46 patients with acute exacerbation of chronic pulmonary heart disease of the same period were enrolled in group B ......