老年非小细胞肺癌患者细胞免疫功能变化及手术化疗对其影响分析(3)
综上所述,老年非小细胞肺癌患者本身细胞免疫功能会呈现明显下降状态,而手术与化疗会进一步损伤患者的细胞免疫。患者身体免疫系统的调节应作为反映患者预后的指标加以重视。
[参考文献]
[1] Qu HQ, Zhou XS, Zhou XL, et al. Effect of DC-CIK cell on the proliferation, apoptosis and differentiation of leukemia cells[J].Asian Pac J Trop Med,2014,7(8):659-662.
[2] 魏立,陳明耀,务森,等.非小细胞肺癌患者围术期细胞免疫功能的变化及免疫治疗[J].中国胸心血管外科临床杂志,2009,16(4):327-328.
[3] 袁颖.非小细胞肺癌患者外周血T淋巴细胞亚群和Treg的检测及临床意义[D].石家庄:河北医科大学,2013.
[4] 曲爱忠.外周血CD4~+CD25~+调节性T细胞与肿瘤相关性的研究[D].济南:山东大学,2009.
[5] 赵海燕,苏乌云,呼群,等.DC-CIK 联合化疗治疗晚期非小细胞肺癌的疗效及对免疫功能的影响[J].现代生物医学进展,2017,17(13):2560-2564.
[6] Zhao YJ, Jiang N, Song QK, et al. Continuous DC-CIK infusions restore CD8+cellular immunity,physical activity and improve clinical efficacy in advanced cancer patients unresponsive to conventional treatments[J].Asian Pac J Cancer Prev,2015,16(6):2419-2423.
[7] 施博文,乔文亮,韩玉栋,等.非小细胞肺癌免疫治疗的研究进展[J].现代生物医学进展,2016,16(20):3969-3973.
[8] Yuanying Y, Lizhi N, Feng M, et al. Therapeutic outcomes of combining cryotherapy,chemotherapy and DC-CIK immu notherapy in the treatment of metastatic non-small cell l ung cancer [J].Cryobiology,2013,67(2):235-240.
(收稿日期:2017-11-29), http://www.100md.com(辛本强 邢加强)
[参考文献]
[1] Qu HQ, Zhou XS, Zhou XL, et al. Effect of DC-CIK cell on the proliferation, apoptosis and differentiation of leukemia cells[J].Asian Pac J Trop Med,2014,7(8):659-662.
[2] 魏立,陳明耀,务森,等.非小细胞肺癌患者围术期细胞免疫功能的变化及免疫治疗[J].中国胸心血管外科临床杂志,2009,16(4):327-328.
[3] 袁颖.非小细胞肺癌患者外周血T淋巴细胞亚群和Treg的检测及临床意义[D].石家庄:河北医科大学,2013.
[4] 曲爱忠.外周血CD4~+CD25~+调节性T细胞与肿瘤相关性的研究[D].济南:山东大学,2009.
[5] 赵海燕,苏乌云,呼群,等.DC-CIK 联合化疗治疗晚期非小细胞肺癌的疗效及对免疫功能的影响[J].现代生物医学进展,2017,17(13):2560-2564.
[6] Zhao YJ, Jiang N, Song QK, et al. Continuous DC-CIK infusions restore CD8+cellular immunity,physical activity and improve clinical efficacy in advanced cancer patients unresponsive to conventional treatments[J].Asian Pac J Cancer Prev,2015,16(6):2419-2423.
[7] 施博文,乔文亮,韩玉栋,等.非小细胞肺癌免疫治疗的研究进展[J].现代生物医学进展,2016,16(20):3969-3973.
[8] Yuanying Y, Lizhi N, Feng M, et al. Therapeutic outcomes of combining cryotherapy,chemotherapy and DC-CIK immu notherapy in the treatment of metastatic non-small cell l ung cancer [J].Cryobiology,2013,67(2):235-240.
(收稿日期:2017-11-29), http://www.100md.com(辛本强 邢加强)