[摘要] 目的 分析比阿培南治疗中重症细菌性感染的临床疗效。方法 随机抽选2015年1月—2018年1月间该院接收治疗的80例重症细菌性感染患者，以随机法分组：40例予以比阿培南治疗的为治疗组，40例予以美罗培南治疗的为对照组，对比2组临床疗效。结果 治疗后，40例治疗组有效率90.00%、细菌消除率90.10%，与40例对照组的87.50%(χ2=0.125；P=0.723)、88.46%(χ2=0.853；P=0.356)相比，差异无统计学意义(P>0.05)；对照组中8例发生不良反应症状，而治疗组中仅2例发生(χ2=4.114；P=0.043)。结论 重症细菌性感染患者治疗期间选比阿培南、美罗培南展开治疗，两种方法疗效相当，但比阿培南应用起来安全性要更高，值得推广。

    [关键词] 比阿培南；细菌性感染；治疗效果

    [中图分类号] R515 [文献标识码] A [文章编号] 1674-0742(2018)05(b)-0110-03

    [Abstract] Objective This paper tries to analyze the clinical efficacy of biapenem in the treatment of severe bacterial infections. Methods 80 patients with severe bacterial infections received and treated in this hospital between January 2015 and January 2018 were selected. They were randomly divided into two groups： 40 patients treated with biapenem as treatment group and 40 patients treated with meropenem and compared the clinical efficacy of the 2 groups. Results After treatment ......