FGF21与非酒精性脂肪性肝病和糖尿病相关性的研究进展(4)
[16] Jiang S, Yan C, Fang QC, et al. Fibroblast growth factor 21 is regulated by the IRE1alpha-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis[J].J Biol Chem, 2014(289): 29751-29765.
[17] Xu J, Lloyd DJ, H ale C, et al. Fibrob last growth factor 21 reverses hepatic steatosis, increases energy expend iture, and improves insulin sensitivity indiet induced obese mice[J].D iabetes, 2009,58(1):250-259.
[18] Kim SH.Fibroblast growth factor 21 participates in adapta tion to endoplasmic reticulum stress and attenuates obesity-induced hepatic metabolic stress[J].Diabetologia,2015,58(4):809-818.
[19] Veniant MM, et a1.FGF21 promotes metabolic homeostasis via white adipose and leptin in mice[J].PLoS One,2012,7(7):40164.
[20] VFenni Rusli, Joris Deelen, Evi Andriyani,et al. Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice[J].Sci Rep,2016,6:30484.
(收稿日期:2018-05-21), 百拇医药(柴学峰 王国君)
[17] Xu J, Lloyd DJ, H ale C, et al. Fibrob last growth factor 21 reverses hepatic steatosis, increases energy expend iture, and improves insulin sensitivity indiet induced obese mice[J].D iabetes, 2009,58(1):250-259.
[18] Kim SH.Fibroblast growth factor 21 participates in adapta tion to endoplasmic reticulum stress and attenuates obesity-induced hepatic metabolic stress[J].Diabetologia,2015,58(4):809-818.
[19] Veniant MM, et a1.FGF21 promotes metabolic homeostasis via white adipose and leptin in mice[J].PLoS One,2012,7(7):40164.
[20] VFenni Rusli, Joris Deelen, Evi Andriyani,et al. Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice[J].Sci Rep,2016,6:30484.
(收稿日期:2018-05-21), 百拇医药(柴学峰 王国君)