体表心电图TpTe间期及TpTe/QT对Br S患者恶性室性心律失常的预测效能分析(1)
[摘要] 目的 探究體表心电图T波顶点到T波终点之间的时间(TpTe)间期及TpTe间期与从QRS波起始至T波终点的时间的比值(TpTe/QT)在Brugada综合征(Br S)患者恶性室性心律失常预测中的应用价值。方法 便利2018年1—12月该院收治的Br S患者21例为研究对象，其中恶性室性心律失常患者9例为研究组，其余12例为对照组，对比两组患者TpTe、QT间期和TpTe/QT。 结果 研究组患者V2导联的TpTe/QT、TpTe间期分别为0.32和(108.68±11.23)ms，对照组患者则分别为0.23和(83.97±5.94)ms，两组差异有统计学意义(P<0.05)，两组其他导联间期则差异无统计学意义(P>0.05);TpTe/QT、TpTe间期ROC曲线下面积分别为0.971、0.892;TpTe/QT≥0.257对Br S患者恶性室性心律失常预测的特异度和灵敏度分别为0.931和0.883，TpTe间期≥95 ms预测的特异度和灵敏度分别为0.821和0.882。结论 体表心电图TpTe间期及TpTe/QT可以良好预测Br S患者的恶性室性心律失常情况，TpTe/QT≥0.257及TpTe间期≥95 ms提示患者可能出现恶性室性心律失常。
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[关键词] 体表心电图;TpTe间期;TpTe/QT;Brugada综合征;恶性室性心律失常
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2019)07(c)-0191-03
Predictive Efficacy of Surface Electrocardiogram TpTe Interval and TpTe/QT on Malignant Ventricular Arrhythmia in Patients with Br S
BAO Jian-min
Department of Cardiology， Third People's Hospital of Hubei Province， Wuhan， Hubei Province， 430030 China
, 百拇医药
[Abstract] Objective To investigate the ratio of the time between the T wave apex of the surface electrocardiogram to the end of the T wave (TpTe) interval and the time between the TpTe interval and the time from the start of the QRS wave to the end of the T wave (TpTe/QT) in Brugada synthesis. The value of the application of predicting malignant ventricular arrhythmia in patients with signs of (Br S). Methods 21 patients with Br S admitted to our hospital from January to December 2018 were enrolled. Among them， 9 patients with malignant ventricular arrhythmia were in the study group， and the remaining 12 patients were in the control group. TpTe， QT interval and TpTe/QT was compared between the two groups. Results The TpTe/QT and TpTe intervals of the V2 lead in the study group were 0.32 and (108.68±11.23) ms， respectively， and those in the control group were 0.23 and (83.97±5.94) ms， respectively. The difference between the two groups was significant (P<0.05). There was no significant difference in the other lead intervals between the two groups (P>0.05). The area under the ROC curve of TpTe/QT and TpTe interval was 0.971 and 0.892， respectively. The prediction of malignant ventricular arrhythmia in patients with Br S by TpTe/QT≥0.257. The specificity and sensitivity were 0.931 and 0.883， respectively， and the specificity and sensitivity of the predicted TpTe interval ≥95 ms were 0.821 and 0.882， respectively. Conclusion Surface electrocardiogram TpTe interval and TpTe/QT can predict malignant ventricular arrhythmia in patients with Br S， TpTe/QT≥0.257 and TpTe interval ≥95 ms suggest that patients may have malignant ventricular arrhythmia., http://www.100md.com(包健敏)
, http://www.100md.com
[关键词] 体表心电图;TpTe间期;TpTe/QT;Brugada综合征;恶性室性心律失常
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2019)07(c)-0191-03
Predictive Efficacy of Surface Electrocardiogram TpTe Interval and TpTe/QT on Malignant Ventricular Arrhythmia in Patients with Br S
BAO Jian-min
Department of Cardiology， Third People's Hospital of Hubei Province， Wuhan， Hubei Province， 430030 China
, 百拇医药
[Abstract] Objective To investigate the ratio of the time between the T wave apex of the surface electrocardiogram to the end of the T wave (TpTe) interval and the time between the TpTe interval and the time from the start of the QRS wave to the end of the T wave (TpTe/QT) in Brugada synthesis. The value of the application of predicting malignant ventricular arrhythmia in patients with signs of (Br S). Methods 21 patients with Br S admitted to our hospital from January to December 2018 were enrolled. Among them， 9 patients with malignant ventricular arrhythmia were in the study group， and the remaining 12 patients were in the control group. TpTe， QT interval and TpTe/QT was compared between the two groups. Results The TpTe/QT and TpTe intervals of the V2 lead in the study group were 0.32 and (108.68±11.23) ms， respectively， and those in the control group were 0.23 and (83.97±5.94) ms， respectively. The difference between the two groups was significant (P<0.05). There was no significant difference in the other lead intervals between the two groups (P>0.05). The area under the ROC curve of TpTe/QT and TpTe interval was 0.971 and 0.892， respectively. The prediction of malignant ventricular arrhythmia in patients with Br S by TpTe/QT≥0.257. The specificity and sensitivity were 0.931 and 0.883， respectively， and the specificity and sensitivity of the predicted TpTe interval ≥95 ms were 0.821 and 0.882， respectively. Conclusion Surface electrocardiogram TpTe interval and TpTe/QT can predict malignant ventricular arrhythmia in patients with Br S， TpTe/QT≥0.257 and TpTe interval ≥95 ms suggest that patients may have malignant ventricular arrhythmia., http://www.100md.com(包健敏)