免疫球蛋白水平在慢性乙型肝炎患者检验中的意义分析(1)
[摘要] 目的 分析慢性乙型肝炎患者檢验免疫球蛋白指标的变化及其在临床治疗中发挥的价值。方法 方便选择2015年1月—2019年2月该院收治慢性乙型肝炎患者112例，参照患者病情分为A、B两组，A组56例患者为慢性乙型肝炎疾病，B组56例患者为慢性重型乙型肝炎疾病，另外选择同期于该院门诊接受体检的健康者60名为C组，对比各组人员免疫球蛋白指标差异。根据患者病情进展划分为好转组及非好转组，对各组患者免疫球蛋白指标、总胆红素指标进行比较。 结果 B组患者IgG指标(16.84±1.26)g/L、IgA指标(2.96±0.24)g/L、IgM指标(2.87±0.16)g/L均明显高于A组与C组(F=11.270、21.890、23.470，P<0.05)，且A组患者相应指标明显高于C组(P<0.05)，另外好转组患者IgG指标(13.14±1.21)g/L、IgA指标(2.31±0.02)g/L、IgM指标(2.59±0.22)g/L、TBIL指标(169.46±12.11)μmol/L、均明显低于非好转组(t=7.260、8.140、10.580、8.260，P<0.05)。 结论 慢性乙型肝炎患者病情均可通过免疫球蛋白指标、总胆红素指标显示，能够为临床后续治疗提供数据参考。
[关键词] 免疫球蛋白;慢性乙型肝炎;总胆红素;IgG
[中图分类号] R446 [文献标识码] A [文章编号] 1674-0742(2019)11(a)-0172-03
Significance of Immunoglobulin Levels in the Examination of Patients with Chronic Hepatitis B
JI Tong-jun
Yancheng Dafeng People's Hospital， Yancheng， Jiangsu Province， 224100 China
[Abstract] Objective To analyze the changes of immunoglobulin index in patients with chronic hepatitis B and its value in clinical treatment. Methods From January 2015 to February 2019， Convenient selected 112 patients with chronic hepatitis B were enrolled in the hospital. The patients were divided into two groups according to the patient's condition. 56 patients in group A were chronic hepatitis B disease， group B of 56 patients were chronic severe hepatitis B disease. In addition， 60 healthy subjects who underwent physical examination in our hospital at the same time were selected as group C， and the differences in immunoglobulin indexes between the groups were compared. According to the patient's progress， the patients were divided into the improvement group and the non-improvement group， and the immunoglobulin index and total bilirubin index of each group were compared. Results The IgG index (16.84±1.26) g/L， IgA index (2.96±0.24) g/L and IgM index (2.87±0.16) g/L in group B were significantly higher than those in group A and C(F=11.270， 21.890， 23.470， P<0.05)， and the corresponding indexes in group A were significantly higher than those in group C(P<0.05)， in addition， the IgG index (13.14±1.21) g/L， IgA index (2.31±0.02)g/L， IgM index (2.59±0.22) g/L， and TBIL index (169.46±12.11)μmol/L in the improved group were all obvious， lower than the non-improved group (t=7.260， 8.140， 10.580， 8.260， P<0.05). Conclusion The condition of patients with chronic hepatitis B can be indicated by immunoglobulin index and total bilirubin index， which can provide data reference for clinical follow-up treatment., 百拇医药(季通军)
[关键词] 免疫球蛋白;慢性乙型肝炎;总胆红素;IgG
[中图分类号] R446 [文献标识码] A [文章编号] 1674-0742(2019)11(a)-0172-03
Significance of Immunoglobulin Levels in the Examination of Patients with Chronic Hepatitis B
JI Tong-jun
Yancheng Dafeng People's Hospital， Yancheng， Jiangsu Province， 224100 China
[Abstract] Objective To analyze the changes of immunoglobulin index in patients with chronic hepatitis B and its value in clinical treatment. Methods From January 2015 to February 2019， Convenient selected 112 patients with chronic hepatitis B were enrolled in the hospital. The patients were divided into two groups according to the patient's condition. 56 patients in group A were chronic hepatitis B disease， group B of 56 patients were chronic severe hepatitis B disease. In addition， 60 healthy subjects who underwent physical examination in our hospital at the same time were selected as group C， and the differences in immunoglobulin indexes between the groups were compared. According to the patient's progress， the patients were divided into the improvement group and the non-improvement group， and the immunoglobulin index and total bilirubin index of each group were compared. Results The IgG index (16.84±1.26) g/L， IgA index (2.96±0.24) g/L and IgM index (2.87±0.16) g/L in group B were significantly higher than those in group A and C(F=11.270， 21.890， 23.470， P<0.05)， and the corresponding indexes in group A were significantly higher than those in group C(P<0.05)， in addition， the IgG index (13.14±1.21) g/L， IgA index (2.31±0.02)g/L， IgM index (2.59±0.22) g/L， and TBIL index (169.46±12.11)μmol/L in the improved group were all obvious， lower than the non-improved group (t=7.260， 8.140， 10.580， 8.260， P<0.05). Conclusion The condition of patients with chronic hepatitis B can be indicated by immunoglobulin index and total bilirubin index， which can provide data reference for clinical follow-up treatment., 百拇医药(季通军)