心脏复苏中应用多巴胺与肾上腺素合用的价值探讨(1)
[摘要] 目的 探讨心脏复苏中应用多巴胺与肾上腺素合用的价值。 方法 方便选取2018年1月—2019年10月在该院进行心脏复苏治疗的96例患者为该次研究对象，根据治疗方法的不同分为两组，对照组和研究组各48例。对照组应用肾上腺素治疗，研究组应用多巴胺与肾上腺素合用治疗，对比两组患者治疗后的结果以及各项指标评分。 结果 研究组患者心电活动恢复率72.9%、自主循环恢复率68.8%均高于对照组心电活动恢复率47.9%、自主循环恢复率41.7%(χ2=6.272、5101，P<0.05)。治疗后研究组患者的SaO2、PaCO2以及PaO2动脉血气指标改善均优于对照组(t=19.215、20.571、19.255，P<0.05)。 结论 多巴胺与肾上腺素在心脏复苏中联合使用取得了理想的效果，能够提高患者的电活动恢复率、自主循环恢复率，同时有效的改善了患者的动脉血气指标，在一定程度上改善了心脏骤停患者预后差的问题。
[关键词] 心脏复苏;多巴胺;肾上腺素;心电活动;自主循环
[中图分类号] R541 [文献标识码] A [文章编号] 1674-0742(2020)10(a)-0094-03
Discussion on the Value of Dopamine and Adrenaline in Cardiac Resuscitation
ZHONG Qi， JIANG Jun， MENG Guo-sheng， YU Ning
Emergency Department， Laibin People's Hospital Region， Laibin， Guangxi Zhuang Autonomous， 546100 China
[Abstract] Objective To explore the value of dopamine combined with adrenaline in cardiac resuscitation. Methods Ninety-six patients who underwent cardiac resuscitation in the hospital from January 2018 to October 2019 were conveniently selected as the subjects of this study. According to the different treatment methods， they were divided into two groups， the control group and the study group with 48 cases each. The control group was treated with epinephrine， and the study group was treated with dopamine and epinephrine. The results of the two groups of patients after treatment and the scores of various indicators were compared. Results The recovery rate of ECG activity and the recovery rate of spontaneous circulation of 72.9% and 68.8% of the study group were higher than those of the control group’s47.9% and 41.7% (χ2=6.272， 5.101， P<0.05). After treatment， the improvement of the SaO2， PaCO2 and PaO2 arterial blood gas index of the study group was better than that of the control group (t=19.215， 20.571， 19.255， P<0.05). Conclusion The combined use of dopamine and epinephrine in cardiac resuscitation has achieved ideal results. It can improve the patient’s electrical activity recovery rate and spontaneous circulation recovery rate， while effectively improving the patient’s arterial blood gas indicators， and improving cardiac agitation to a certain extent. The problem of poor prognosis for patients with discontinuation should be further promoted.
[Key words] Cardiac resuscitation; Dopamine; Adrenaline; Cardiac electrical activity; Spontaneous circulation
心臟骤停是指患者的心脏射血功能突然终止，导致患者的脑组织等器官出现缺氧、缺血的情况，并引起大动脉的搏动、心音等消失，是一种高危的急症。心肺复苏是心脏发生骤停时采取的急救措施，在临床中有着积极的意义[1]。有关数据表示，心脏骤停4 min后就会对脑组织造成严重的伤害，超过10 min就会引起脑死亡，具有极高的病死率，严重威胁着患者的生命安全。因此在发生心脏骤停后，给予患者积极有效的心脏复苏对患者的预后有着重要的影响作用[2]。肾上腺素是常用的心脏复苏药物，在心脏骤停的复苏中起着重要的作用，但是有关数据显示单用肾上腺素的整体效果并不是很理想，复苏率较低而且复苏成功后的预后较差。有研究发现，在心脏复苏中应用肾上腺素联合多巴胺的效果会更好[3]。该文为探讨心脏复苏中应用多巴胺与肾上腺素合用的价值，现方便选取2018年1月—2019年10月在该院进行过心脏复苏治疗的96例患者作为研究对象，报道如下。, 百拇医药(钟旗 江俊 蒙国升 俞宁)
[关键词] 心脏复苏;多巴胺;肾上腺素;心电活动;自主循环
[中图分类号] R541 [文献标识码] A [文章编号] 1674-0742(2020)10(a)-0094-03
Discussion on the Value of Dopamine and Adrenaline in Cardiac Resuscitation
ZHONG Qi， JIANG Jun， MENG Guo-sheng， YU Ning
Emergency Department， Laibin People's Hospital Region， Laibin， Guangxi Zhuang Autonomous， 546100 China
[Abstract] Objective To explore the value of dopamine combined with adrenaline in cardiac resuscitation. Methods Ninety-six patients who underwent cardiac resuscitation in the hospital from January 2018 to October 2019 were conveniently selected as the subjects of this study. According to the different treatment methods， they were divided into two groups， the control group and the study group with 48 cases each. The control group was treated with epinephrine， and the study group was treated with dopamine and epinephrine. The results of the two groups of patients after treatment and the scores of various indicators were compared. Results The recovery rate of ECG activity and the recovery rate of spontaneous circulation of 72.9% and 68.8% of the study group were higher than those of the control group’s47.9% and 41.7% (χ2=6.272， 5.101， P<0.05). After treatment， the improvement of the SaO2， PaCO2 and PaO2 arterial blood gas index of the study group was better than that of the control group (t=19.215， 20.571， 19.255， P<0.05). Conclusion The combined use of dopamine and epinephrine in cardiac resuscitation has achieved ideal results. It can improve the patient’s electrical activity recovery rate and spontaneous circulation recovery rate， while effectively improving the patient’s arterial blood gas indicators， and improving cardiac agitation to a certain extent. The problem of poor prognosis for patients with discontinuation should be further promoted.
[Key words] Cardiac resuscitation; Dopamine; Adrenaline; Cardiac electrical activity; Spontaneous circulation
心臟骤停是指患者的心脏射血功能突然终止，导致患者的脑组织等器官出现缺氧、缺血的情况，并引起大动脉的搏动、心音等消失，是一种高危的急症。心肺复苏是心脏发生骤停时采取的急救措施，在临床中有着积极的意义[1]。有关数据表示，心脏骤停4 min后就会对脑组织造成严重的伤害，超过10 min就会引起脑死亡，具有极高的病死率，严重威胁着患者的生命安全。因此在发生心脏骤停后，给予患者积极有效的心脏复苏对患者的预后有着重要的影响作用[2]。肾上腺素是常用的心脏复苏药物，在心脏骤停的复苏中起着重要的作用，但是有关数据显示单用肾上腺素的整体效果并不是很理想，复苏率较低而且复苏成功后的预后较差。有研究发现，在心脏复苏中应用肾上腺素联合多巴胺的效果会更好[3]。该文为探讨心脏复苏中应用多巴胺与肾上腺素合用的价值，现方便选取2018年1月—2019年10月在该院进行过心脏复苏治疗的96例患者作为研究对象，报道如下。, 百拇医药(钟旗 江俊 蒙国升 俞宁)